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The original digging number is included in the topic # 44 migrant workers.

In recent weeks, I have a toothache. According to past experience, either my gums are severely atrophied or my teeth are cracked and need to be filled. So I hung up the number of a famous dental hospital in Guangzhou with my mobile phone, which was particularly difficult to hang up. It was full in recent days and I could only hang up the number four days later.

At 7 o’clock this morning, it was drizzling in the sky. I set off for the hospital, filled out a form to take a temperature measurement, and wanted to know whether the dental insurance could be reported at the registration office. I saw a buddy in front of me paying money, the first one was more than 6,700, and the second one was more than 1,900. I was so scared that I almost wanted to go home, but I wanted to come all over again. The dentistry was so profitable that I had to dig it.

At 8: 30, there were a lot of people sitting at the door. The hospital was not big, but there were departments in the elevator. I was looking at the dental pulp department.

On a whim, I want to see the flow distribution of people in various departments at this time, and I ran a circle on the upper and lower floors:

6F Children’s Stomatology: 1 person

5F Orthodontics Department: 8 people, Dental Pulp Department: 8 people.

4F Implant and Prosthetic Department: 8 people, Oral and Maxillofacial Surgery: 6 people.

1F Radiology Department: 5 people, Periodontology Department: 9 people.

(Not included in the treatment)

It’s my turn. After checking, it was concluded that a tooth needs to be filled. After paying the total fee of 305, I paid 200 medical insurance for reimbursement of 105. I just saw the expenses of various projects on the screen of the hall, and took a photo.

How to estimate the annual income of this hospital? It is known that the maximum number of doctors registered in a day is 30. From the registration applet, we can see that the number here is full almost every day, and we can see how many doctors there are in each department every day.

The number of patients per day can be calculated as follows:

Pediatric stomatology: 6 doctors *30 numbers =180 people.

Oral and Maxillofacial Surgery: 5 doctors *30 numbers =150 people

Orthodontics: 7*30=210 people

Dental and endodontic department: 9*30=270 people

Periodontal disease department: 5*30=150 people

Implant Restoration Section: 5*30=150 people

According to this number of people, the registration fee alone can earn 10 yuan *1110 people =11100 yuan per day, which is really cool!

The total income can be estimated if there is another per capita cost. My idea is to take the cost of the most common treatment items in each department instead of the per capita cost. For example, periodontal disease is tooth cleaning, and dental pulp is tooth filling. Combined with the cost photographed in the hall and online data, some common treatments, such as tooth cleaning, pulling out a wisdom tooth, applying fluoride to the whole mouth, filling a tooth, etc., cost about 500. Roughly speaking, if 500 yuan is taken as the per capita cost, then the hospital’s annual income.

500 yuan *1110 people/day *365 days = about 200 million.

This hospital is only a small branch. If it is the General Hospital, it is estimated that its income will double. According to the hospital’s WeChat WeChat official account, there are 50 doctors here, which means that each doctor brings 200 million /50=4 million in revenue every year.

With such a high per capita income, it can be inferred that the income of dentists should be high. Digging through the financial report of a dental A-share listed company, which has 21 dental hospitals in Zhejiang, there are several interesting data in the financial report:

For example, the annual revenues of the above four stomatological hospitals are 620 million, 390 million, 140 million and 40 million respectively, and the net profit margins are 40%, 28%, 28% and 16% respectively.

For example, 54.99% of the cost of stomatological hospital is labor cost, which proves the high income of dentists.

So how high is the income of dentists? I searched a lot of answers in Zhihu. The monthly salary of dentists in public hospitals in first-and second-tier cities is between 10,000 and 20,000, and 30,000 to 40,000 if they are deputy directors or above.

Data reference from: https://www.zhihu.com/question/364101818/answer/958783096

Dentists in private hospitals earn more. Here is an authoritative data, which comes from the dictation of the founder of a dentist online platform:

At present, private dental hospitals basically adopt the salary method of basic salary plus commission. The monthly income of dentists with lower income is about 20,000 to 30,000 yuan, and the monthly income of dentists with higher income can reach 60,000 to 70,000 yuan. Some top dentists will have a higher commission, and may even break 500,000 yuan a month.

As we are now, we basically recruit doctors from some good public hospitals such as Huaxi Stomatology, and the success rate is still relatively high, because in private clinics, especially brand-operated private clinics, the treatment is also better, and the recognition of doctors in the industry is not worse than that in public hospitals.

He also mentioned that there is a great demand for dentists in China:

The ratio of dentists to population is only 1: 28,000, compared with 1: 1,000 in developed countries such as the United States, 1: 2,000 in Japan and 1: 4,000 in Western Europe, which fully shows that there is a great gap in the demand for dentists in China.

Source: https://www.iyiou.com/analysis/2018052373041.

I really envy, envy and hate. The key dentist is still a profession that gets more and more popular as he gets older. He will not retire at the age of 35 like the siege lion, and he has a high sense of security!

Original title: "How much can a dental clinic earn a year? 》

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　　Guangxi Baziling Great Wall VS Beijing Badaling Great Wall

　　Built in imitation of the Badaling Great Wall in Beijing, the Baziling Great Wall in Luchuan County, Yulin City, Guangxi Province quickly became popular and became a popular "punch-in" point for local people. On the 23rd, the reporter went to Luchuan County to visit this building which was called the Guangxi version of the "Great Wall" by netizens.

　　On November 23rd, aerial photography was taken of the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Starting from Luchuan County, it takes about an hour to drive to the Guiling Valley rural tourist area located in Baziling, Gao Qing Village, Shapo Town, Luchuan County, Yulin City. The gate of the scenic spot is a "Little Great Wall" built after the Badaling Great Wall, and the words "The Great Wall for Sightseeing in the Guling Valley" are impressive.

　　On November 23, tourists took photos at the "Baziling Great Wall" in the rural tourist area of Guilinggu, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Climb up the stone steps and come to the highest "beacon tower" of the "Baziling Great Wall", surrounded by mountains and sometimes misty clouds. From afar, you can see Xiexianzhang, the highest mountain in Luchuan County. As can be seen from the aerial picture, the "Baziling Great Wall" is shaped like a "eight" and extends to both sides.

　　On November 23rd, aerial photography was taken of the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　It was named "Baziling Great Wall" because it was built in Baziling.

　　Ruan Guansheng, the person in charge of Guilinggu Rural Tourism Zone, introduced that the "Baziling Great Wall" project was built under the guidance of Luchuan County Party Committee and Government, and efforts were made to create a new bright spot in the combination of industrial poverty alleviation and rural tourism. The project is planned to build 2000 meters. At present, the first phase of the project has been completed 450 meters, and the trial operation began during the National Day holiday this year.

　　Ruan Guansheng introduced that the "Baziling Great Wall" is actually a sightseeing corridor in the tourist area, named after it was built on the local Baziling. Before the project construction, it has been approved by Luchuan County Environmental Protection Bureau.

　　Ruan Guansheng said that the "Baziling Great Wall" was built on the ridge, which was originally a forest fire zone with sparse vegetation. Mountain fires often occur in the local area. After the "Baziling Great Wall" is repaired, Gao Qing Village and Bei ‘an Village on both sides will be separated to play the role of isolation and fire prevention. Considering the problem of environmental protection, the cement sand used in the construction of the "Baziling Great Wall" is all carried up the mountain by horses.

　　On November 23, tourists took photos at the "Baziling Great Wall" in the rural tourist area of Guilinggu, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Quickly became popular and controversial.

　　Ruan Guansheng introduced that the "Baziling Great Wall" began trial operation during the National Day holiday this year, which attracted many tourists to visit and visit, and the small holiday received about 35,000 tourists. "At that time, tourists were full and meals were in short supply."

　　The reporter noticed that on the network platform, the topic of "high imitation of the Great Wall" has attracted the attention of many netizens. Netizens have different views on the "high imitation of the Great Wall". Some people think it is a "knockoff", which has no historical connotation and is meaningless. Some people think that it is good to climb the Great Wall in Guangxi.

　　On the 23rd, there was an endless stream of tourists visiting the "Baziling Sightseeing Great Wall". People have taken photos at the "Haohanpo" of the "Baziling Great Wall".

　　On November 23, tourists took photos at the "Baziling Great Wall" in the rural tourist area of Guilinggu, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Xie Xiaoqin, a tourist from Yulin City, said that it is not surprising that the "Baziling Sightseeing Great Wall" attracted attention because it imitated the famous Badaling Great Wall. But it doesn’t have the cultural background of Badaling Great Wall, and it doesn’t tap the local characteristics. It’s hard to say how long it will be popular.

　　Ms. Luo, a tourist from Guangzhou, has been to the Badaling Great Wall in Beijing. She thinks that the "Baziling Great Wall" can’t be compared with the Badaling Great Wall, but for local people, the construction of the "Little Great Wall" can bring new leisure tourism projects, which is also good.

　　On November 23rd, tourists visited the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　The project leader responds to the dispute.

　　Ruan Guansheng doesn’t care about these disputes. Ruan Guansheng said that the Great Wall of Wan Li is a famous tourist attraction and a place that Chinese yearns for. When she was in her seventies, my mother urged me to take her to the Badaling Great Wall in Beijing. However, it is a long way from Guangxi to Beijing and the cost is high. Many people, especially the elderly, rarely have the opportunity to experience climbing the Great Wall.

　　On November 23rd, aerial photography was taken of the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Ruan Guansheng introduced that Gao Qing Village is one of the second batch of key rural tourism villages in China. The rural tourism project of Guilinggu, located in Baziling, Gao Qing Village, covers an area of more than 130 hectares, and is planted with economic trees such as camellia oleifera, orange peel and camellia chrysantha, with an original ecological forest landscape stretching for dozens of miles, forming a new development path of "characteristic industry+characteristic tourism".

　　Over the years, Guilinggu Rural Tourism Zone has absorbed 72 poor households in the village to participate in rural tourism poverty alleviation industry, and implemented the model of villagers’ cooperatives+tourism enterprises+poor households to develop and expand tourism, providing a platform for poor households to get rid of poverty and increase their income.

　　On November 23rd, aerial photography was taken of the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Ruan Guansheng is a native of Gao Qing village. He worked in architecture in his early years and has some experience. He thought that Baziling Mountain was very suitable for building a sightseeing corridor, so he came up with the idea of building a condensed version of the Great Wall. "One is to satisfy the villagers’ desire to climb the Great Wall, and the other is to increase the attractions for rural tourism and promote tourism development, thus helping poor households to increase their income."

　　On November 23rd, tourists visited the "Baziling Great Wall" in Guilinggu rural tourist area, Luchuan County, Guangxi. Photo by Chen Guanyan

　　Ruan Guansheng said that Luchuan County has a good geographical location. In September this year, the Yulin-Zhanjiang Expressway in Guangxi was fully opened to traffic, making it very convenient for Guangdong tourists to travel to Luchuan County by car. In the future, the "Baziling Great Wall" will attract more tourists from Guangdong Province and even all over the country to experience it. "We are accelerating the improvement of tourism infrastructure and preparing for receiving more tourists."

　　Author: Chen Qiuxia Chen Guanyan

yuan

Yuan Dynasty (1206-1368)

xiao

night

jie

festival

February 26th, 2021 is the Lantern Festival, which is near the weekend. During the holidays, people and vehicles flow heavily. In order to ensure the safe and smooth road traffic during the holidays and create a good road traffic safety environment for celebrating the festival, the Traffic Management Bureau of Jilin Provincial Public Security Department issued the "Lantern Festival Two Announcements and One Prompt" in Changchun City, asking the majority of traffic participants to reasonably choose travel time, travel routes and travel modes, avoid travel peaks and easy-to-block sections, drive safely and travel safely.

Weather conditions during the Lantern Festival

During the Lantern Festival, expressways are not free. According to the "Implementation Plan for Exempting Small Bus Tolls for Major Holidays", the policy of free passage of 7-seat (including 7-seat) small bus expressways will be implemented for four national statutory holidays: Spring Festival, Tomb-Sweeping Day, Labor Day and National Day.

Prediction of traffic flow during Lantern Festival

It is estimated that the population flow in the Lantern Festival in 2021 is significantly lower than that in previous years, and there is a strong uncertainty in traffic flow. Before the holiday, the traffic flow will be relatively dispersed, and after the holiday, it will be more concentrated, and the road traffic flow in the bustling business district will increase greatly.

Traffic safety tips for Lantern Festival

1. During the Lantern Festival, family reunions with relatives and friends and short trips increase. Drivers are requested to travel at the wrong peak as much as possible. In case of traffic congestion, please obey the traffic police’s command, do not force traffic jams, and do not fight for roads.

2. Friends get together to celebrate the Lantern Festival and drink more. Drinking alcohol will lead to slow response and slow action, and the driver’s ability to control the vehicle will decrease. For the safety of you and others, please remember "drink without driving, drive without drinking!"

3. Take part in the Lantern Festival folk celebrations. Never drive or take overcrowded minivans or passenger vehicles. Never take tractors, low-speed trucks or illegally operate "black cars" to travel.

4. When driving minivans and passenger vehicles through icy wading roads, please keep driving at a constant speed, keep a distance from the vehicle in front, and do not brake suddenly to avoid side slip.

5. There are many people in tourist attractions, so drivers should pay attention to civility and courtesy, obey traffic signals, don’t make a sharp turn at intersections or narrow sections without traffic lights, and pay attention to slowing down when driving through crosswalks or intersections to avoid unnecessary traffic injuries.

6. During the festival, the traffic volume is heavy. If there is a traffic accident, please call the police in time. If there are no casualties and minor traffic accidents, you should leave the scene immediately after taking photos, and drive to an open place to negotiate or call the police for handling, so as to prevent traffic congestion or secondary accidents; If there are casualties, protect the scene, rescue them in time, and call the police immediately. Don’t be lucky enough to escape.

Expressway driving tips

First, prevent the car from being in bad condition

Before leaving the vehicle, check the vehicle and keep it in good condition.

Second, prevent improper overtaking of passing cars

Try to avoid overtaking, and when passing, the qualified party should take the initiative to stop for courtesy; At night, the lights are used to signal to ensure that they meet slowly under safe conditions.

Third, prevent turning too fast

When turning, you should slow down the speed ahead of time, hold the steering wheel steady and tap it slowly. When the line of sight is not good, turn left to the right as far as possible to expand the driving sight.

Four, prevent braking too fast

Concentrate on driving, try to use predictive braking, and make good use of the engine’s drag to slow down to avoid emergency braking.

The Lantern Festival will remain unchanged.

If you encounter an emergency on the expressway, please call the 24-hour alarm number in time: 0431-12122.

Original title: "Friendly Tips | Don’t forget traffic safety during the Lantern Festival reunion"

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1905 movie network news　"Because the world is round, we will meet again. On the 2307th day after the film was released, Guo Gangtang and his son reunited at the end of 24 years. This is the best ending of the movie. May there be no abduction in the world and no separation in the world. "

　

On July 13th, a press conference was held in the Ministry of Public Security, and it was announced that Guo Zhen (registered as Guo Xinzhen), the prototype of the abducted child of The Lost Orphan, was successfully recovered in the "Reunion Action" and a wedding ceremony was held. After that, the producers of The Lost Orphan released a poster to wish Guo Gangtang and his son a reunion. Lei Zekuan, who plays in the film, also specially recorded videos to express his wishes for the reunion of prototype Guo Gangtang and his son.

Andy Lau said, "Through this lens, I hope to tell Brother Guo that I admire your persistence and pay tribute to the efforts of the public security organs for many years. Here, I appeal to all my friends to join me in supporting the anti-trafficking work and hope that more separated families can reunite as soon as possible. "

In response to this incident, 1905 Film Network contacted the director exclusively at the first time.Peng SanyuanShe revealed that after the news of finding her son in Guo Gangtang was announced, she immediately contacted Guo Gangtang and told Andy Lau. Guo Gangtang replied to her, "Elder sister, I can live a normal life now", and Andy Lau at work quickly replied to her with a smiling face and a prayer gesture expression with his hands folded, very excited.

"Guo Zhen, you may be a little confused about the sudden appearance of your biological father, and you don’t know what to do, but you can learn about your father Guo Gangtang’s 24-year journey through many channels, and every step is love for you, so I wish his appearance is not a burden to you, only love itself!" While posting a message of blessing on the Internet, Peng Sanyuan hoped that Guo Zhen would not have too much psychological burden in the face of his biological father.

　

"I want to say to Guo Zhen, don’t have psychological burden, because for him, Guo Gangtang actually came to him with love 20 years late and blessings from many people." "Don’t think too much, just accept such a late love."Peng Sanyuan believed that Guo Gangtang had been psychologically prepared, because he had said in an interview that he would get along with Guo Zhen’s adoptive parents like relatives, and Guo Zhen’s heart would certainly be shaken, so he didn’t want to be affected too much and change his original life track.

　

Recalling the creative process of "Lonely Lost", Peng Sanyuan said that she began to pay attention to the group of abducted children after seeing the relevant reports of Guo Gangtang in 2010, and contacted the Baby Home Public Welfare Website and the Ministry of Public Security’s Abduction Office successively to track the whole situation of abducted children, and started to create this film after a lot of interviews.

　

The ending of Lost Orphan is that Lei Zekuan, the protagonist, embarks on a straight road and continues his difficult journey of finding relatives. Now prototype father and son finally get together, Peng Sanyuan said frankly:This is the real ending of the movie we expected at that time. We don’t want this father to be on the road forever.

The following is an interview record:

　

1905 Movie Network: Have you contacted the parties after you learned about this matter?

　

Peng Sanyuan:Because we have always had a group in Lost Orphan, including Guo Gangtang, and it is in this group that I posted. I told Gangtang that I was very happy, because he was probably very busy the other day. After he made an appointment, he sent me a short message. He said, Sister, I can live a normal life now.

　

1905 Movie Network: How did you reply?

　

Peng Sanyuan:I have 10,000 joys and 10,000 blessings. I really hope that he can return to a normal life track as soon as possible, live a normal life, and stop running around and suffering.

　

1905 Movie Network: After hearing that you knew about this matter, you contacted Andy Lau at the first time.

　

Peng Sanyuan:Yes, I didn’t tell Brother Hua until Guo Gangtang released the news to the media. I sent him a message. I said that the son of the prototype character of Lonely Lost had been found. He quickly gave me a smiling face and then a gesture of prayer. I guess he might be working at that time.

1905 Movie Network: You wrote an article in Weibo, which was not only a blessing to Guo’s father, but also some words to his son. Why do you think so?

　

Peng Sanyuan:Because Guo Gangtang is psychologically prepared for this matter, and Guo Gangtang has been running for more than 20 years, he is always looking forward to the day when he meets his son, so Guo Gangtang doesn’t need psychological construction, but Guo Zhen is different. He was originally in his own normal growth trajectory, and he didn’t know that he was abducted, so the sudden appearance of this matter should be a shock to him. The reason why he didn’t know, adoptive parents must have never told him that he wasn’t his own. If he had, he would have looked for him. Since he didn’t know, this matter would have been very shocking to him.

　

It takes a psychological time for him to accept Guo Gangtang, so I want to tell Guo Zhen not to have psychological burden, because for him, Guo Gangtang actually came to his side with love that was 20 years late and many people’s blessings. Don’t think too much about whether he should return to his biological parents’ home and how to treat his adoptive parents. I don’t think this should be his psychological burden. He just needs to accept such a late love.

　

I think both Guo Gangtang and Guo Gangtang’s family are wise enough to gradually establish parent-child relationship with their children and get along with their adoptive parents as relatives in the future. Because in previous interviews, Guo Gangtang once said that if he found a child, he hoped to get along with his adoptive parents like relatives. Therefore, Guo Gangtang is prepared, while Guo Zhen is not. I hope he can have a relatively normal life track under such a shocking situation and not change his life track.

1905 Movie Network: We saw Andy Lau,When the main creators sent their blessings, the film also sent a reunion poster. Is there anything different in your heart?

　

Peng Sanyuan:I was particularly moved. This is the real ending we expected at that time. We don’t want this father to be on the road forever. Because our original movie ending gave him a straight way forward, a relatively bright way, and gave him a vision. As the master said, if you do more good deeds, you will meet each other when you get together.

　

Because we can’t answer this question, when can he find Guo Zhen and when can he find his son?In 2037 days after the release of our film, they finally met, or by the efforts of the public security department, the happy ending was realized. For us filmmakers, this ending should be a real ending.

　

1905 Movie Network: From the director’s point of view, does this matter have any influence on your future creation?

　

Peng Sanyuan:I hope that each of our works can help and contribute a little to the society. No matter from which angle, it can promote the progress of the society and the kindness and beauty of the people. We still hope to do something for the society through our own artistic creation, and this original intention will not change.

　　Recently, China’s economic indicators from January to July were released one after another, which aroused a lot of concern.

　　As the largest trading partner of more than 120 countries and regions in the world, the next trend of China’s economy affects the pulse of the global economy.

　　In the past ten years, the air routes of 11 international hub ports along the coast of China have increased by 60%. The maritime service network connects the major ports of more than 100 countries and regions, making it the country with the highest maritime connectivity in the world.

　　At present, the century-old changes and the century-old epidemic are intertwined, and countries around the world are deeply impacted. How should we understand the challenges that China’s economy is experiencing and the expectations of future growth?

　　And how to find the right coordinates to evaluate China’s economy?

　　Master Tan worked out an account with the authority.

01

Which epidemic prevention and control mode has the lowest cost?

A research team of the National Bureau of Statistics has made a model calculation on the relationship between epidemic prevention and control policies, macroeconomic policies and economic loss rate in various countries since the outbreak of the COVID-19 epidemic. The results show that:

　　From 2020 to the first half of 2022, the total economic loss rate of China was only 2.3% under strict prevention and control.

　　However, the economic loss rate under tight prevention and control (such as Japan and South Korea), passive prevention and control (such as Germany and France) and passive prevention and control (such as the United States and Britain) reached 3.9%, 5.5% and 5.9% respectively.

　　At the same time, after excluding the impact of macroeconomic policies, China’s economic loss rate dropped to.floor level.

　　The international media pointed out in an article entitled "China’s policy of" dynamic clearing "of COVID-19 infection contains lessons for other countries" that China’s anti-epidemic policy of "dynamic clearing" has achieved the goal that every country sought two years ago: low mortality and as little economic chaos as possible.

　　China’s epidemic prevention model has been achieved.Give consideration to anti-epidemic and production developmentThe effect.

　　A typical example is that in the first half of this year, China’s export data became the bright spot of growth, while the economic growth expectations of major countries in the world were declining.

　　02 　

　　Why has China become a global lifeline?

　　This is one of the perspectives of epidemic prevention cost accounting. China insists on "dynamic zero clearing", which reduces the manpower, material resources and economic and social costs as much as possible, in exchange for overall economic and social stability.

　　Behind China’s low economic loss rate is the stability and toughness of China’s supply chain and industrial chain under the policy of "dynamic clearing".

　　In the past two years, repeated outbreaks have made this more prominent.

　　Recently, Tan Zhu chatted with Yan Ci, the chief representative of China, the global container shipping logistics giant Maersk Group.

　　The year when Maersk invested in the first fully automated storage project in China was 2020, when the epidemic had just begun.

　　Maersk has a reason to dare to cast this project against the wind.

　　At the China International Fair for Trade in Services in 2020, Yanci praised the company for maintaining normal operation and uninterrupted supply chain with the help of China government.

　　During the epidemic, China fully guaranteed the production of enterprises with a stable soft and hard environment. The goods manufactured in China are continuously transported to the world through logistics companies like Maersk.

　　According to the statistics of the United Nations Conference on Trade and Development,During the epidemic, China’s share of global merchandise exports increased from 13% in 2019 to 15% by the end of 2021..

　　Among them, China’s share in global electronic products exports increased from 38% in 2019 to 42% in 2021, and its share in textile exports increased from 32% to 34%.

　　China’s increased export share has become the "lifeline" for countries such as the United States and Britain to maintain their operations.

　　In 2020, when the epidemic just broke out, 83% of the imported masks in the United States were made in China, two-thirds of the protective clothing came from China, and 90% of the imported box refrigerators specially used for storing vaccines came from China, showing an explosive growth.

　　The epidemic prevention and control in China has stabilized the industrial chain and supply chain, making China a ballast stone to meet the needs of global epidemic prevention, production and life.

　　Stability in the face of wind and rain comes from the accumulation of a sword in ten years.The "Decoding Decade" broadcast by the main station is the best example.

Despite the epidemic, the number of China-Europe trains that are still running smoothly in the Eurasian continent has exploded in this decade, reaching nearly 900 times that of the opening year. Now, there are an average of 42 trains running between China and more than 190 European cities every day.

In the complicated global epidemic situation, stable policies and environment are more attractive, and the keen international capital flow is very convincing.

A few days ago, the Ministry of Commerce announced that from January to July this year, the actual amount of foreign capital used nationwide was 798.33 billion yuan, an increase of 17.3% on a comparable basis.

Investment is confidence.

　　03　　

　　Who has more confidence in China?

　　You can look at the four sources of investment in China highlighted by the Ministry of Commerce:

　　The United States, which has failed to prevent and control the epidemic, has increased its investment in China by 36.3%, and the rest of the countries are also allies that the United States is trying to win over.

　　You know, for a long time in the past, a focus of American diplomacy was to build small courtyards and high walls on the industrial chain with these countries as the axis.

　　But what is it?as the trend of the times indicatesMultinational enterprises have given their choices by voting with their feet.

　　According to the 2022 White Paper on American Enterprises in China released by the American Chamber of Commerce in China this year, more than two-thirds of the member companies continue to list China as the primary market.

　　Starbucks, a Seattle-based coffee chain, is committed to opening 6,000 stores in China before the end of the year.

　　Germany, in the first half of this year, set a record high for its investment in China in the first half of this year since 2000. Among the industries in which Germany increased its investment in China, there was its manufacturing "crown jewel" — — Automobile industry.

　　This year, German Volkswagen, which has been producing and operating in China for nearly 40 years, set the first subsidiary of its software company CARIAD in China — — This is also CARIAD’s first overseas subsidiary.

　　Nearly 40 years ago, the presence of Volkswagen once planted the seeds of growth for China automobile industry.

　　Today, in the eyes of the public, the establishment of a new factory in China, which ranks first in the world in the new energy automobile industry, represents the hope of the public.

　　Bringing the "leader" of China’s top industries to China means more precious confidence besides economic considerations.

　　From a global perspective, the United States, Japan, South Korea and Germany are the economic leaders in America, Asia-Pacific and Europe respectively, and they are also the weathervanes in their regions. Their choices are very convincing.

　　In fact, the Americans themselves have long forgotten: China is one of the countries with the highest total rate of return on foreign direct investment in the United States.

　　According to the U.S. Department of Economic Analysis, from 2000 to 2020, the average rate of return on American direct investment in China is14.7%, much higher than the US overseas direct investment.9.7%Yield.

　　On the contrary, if American companies reduce their investment in China by half, it will cause very direct damage to the American economy, and the one-time loss of gross domestic product (GDP) will be as high as 500 billion US dollars.

　　Even during the COVID-19 epidemic, the overall rate of return of foreign investment in China is still rising. In 2021, foreign investors can still get a rate of return of over 6% when they invest in China.

　　From a longer time dimension, the rate of return on investment in China in 2020 and 2021 remains at a stable level compared with before.

　　Under the epidemic, it remains stable, which is very telling.

　　Pan Yuanyuan, an international investment expert at China Academy of Social Sciences, told Tan Zhu:

　　The first characteristic of foreign direct investment is the long time period; Second, foreign-funded enterprises will also participate in management, bringing their own technology, experience and channels to China, and combining them with China’s resources for transformation. Therefore, unlike short-term speculative investment in the securities market, direct investment pays more attention to the fundamentals of the economy and is also more alert to risks and uncertainties.

　　In other words, the most important thing for foreign direct investment is the stability of a country’s economic expectations.

　　04

　　Where does the stability of China’s economic expectations come from?

　　Recently, the International Monetary Fund also increased the RMB weight in the Special Drawing Rights (SDR) from 10.92% in 2016 to 12.28%.

　　This figure is the confidence of the international community in the stability of China’s economy and financial market, and also the recognition of effective epidemic prevention and control in China.

　　In 2020, under the epidemic crisis, countries’ economic policies to deal with the impact are completely different.

　　Countries represented by the United States, passive prevention and control, but in order to get quick results in the short term, have adopted unlimited quantitative easing policies.

　　From the second quarter of 2020 to the first quarter of 2021, the year-on-year growth rate of M2 in the United States remained above 20%, and the average growth rate of M2 after the epidemic was about 10 percentage points faster than that before the epidemic.

　　Moreover, the United States has repeatedly introduced large-scale economic rescue bills. In 2021, the fiscal deficit ratio reached 12.4%, even higher than the historical high of 9.8% during the financial crisis in 2009.

　　The "strong medicine" seems to be effective quickly, but it has led to bad consequences.

　　During the epidemic, the United States not only ranked among the countries involved in the survey with an economic loss rate of 6.5% (excluding the impact of macroeconomic policies). The more direct performance is that the inflation level in the United States has reached a 41-year high.

Inflation in the United States not only makes American enterprises and consumers bear high production and living costs, but also transfers the crisis to the whole world.

　　According to the assessment of the Bank for International Settlements, the annual inflation rate of nearly 60% developed economies exceeds 5%, the highest level since the late 1980s. The inflation rate of more than 50% developing countries has also exceeded 7%.

　　The rapid interest rate hike by the Federal Reserve in response to inflation has expanded the debt scale of emerging market countries. According to the International Monetary Fund, there are currently 38 developing countries facing debt risks.

　　Under the impact of global inflation and the Federal Reserve’s interest rate hike, Sri Lanka was forced to declare bankruptcy due to "insolvency" and became the first new market country to default on its sovereign debt in 2022.

　　Compared with the strong stimulus measures of the United States, during the epidemic, China’s macroeconomic policies were always guided at a steady pace. In the first half of this year, the national consumer price index (CPI) rose by 1.7% year-on-year, far below the level of European and American countries.

　　Because of this, the US dollar index has risen by more than 11% this year, and the depreciation of the euro, pound and yen against the US dollar is between 10% and 17%. Compared with these major global currencies, the performance of RMB is relatively stable — — It depreciated by about 5.8% against the US dollar.

　　As Lu Jinyong, director of the university of international business and economics Foreign Direct Investment Research Center, said, China still gives people an expectation and hope — — A growth expectation, profit expectation and better and better hope.

　　One of the articles in the international media commenting on China’s economy was titled "China’s economy has hidden power".

　　What are the hidden forces of China’s economy?

　　It is to plan development and safety as a whole, and it is a prominent problem to deal with economic development with systematic concept.

　　It is the wind and waves that are high, but it is as tough as a rock, and it is slow and steady, and it has its own sky.

　　Beijing, China, September 11 (Reporter Tong Yatao) According to World Finance, the economic voice of the Central Radio and Television General Station, the latest data shows that in the first eight months of this year, China’s foreign trade import and export gradually stabilized and improved, and the situation was better than expected. Gao Feng, spokesman of the Ministry of Commerce, said at the press conference held on September 10th that the foreign trade situation this year was supportive and stressful.

　　According to data released by the General Administration of Customs recently, in the first eight months of this year, the total value of China’s foreign trade import and export was 20.05 trillion yuan, down 0.6% from the same period of last year, and the decline was 1.1 percentage points narrower than that in the first seven months. Exports have achieved positive growth, with a year-on-year increase of 0.8%. At the press conference on September 10th, Gao Feng summarized China’s foreign trade performance in the first eight months of this year as "gradually stabilizing and improving, and the situation is better than expected." As for the foreign trade situation this year, Gao Feng used two words to describe it: support and pressure.

　　"On the one hand, it is ‘ Have support ’ . Since the beginning of this year, a series of policies and measures to stabilize foreign trade in the State Council have been continuously implemented, and the policy effects have been continuously released. The demand in the international market has partially picked up, and the PMI index of some major international economies has improved in August. " Gao Feng said, "On the other hand, it is ‘ There is pressure ’ . At present, the global epidemic has not been fully and effectively controlled, and the demand in the international market has shrunk severely. The latest global trade prosperity index released by the WTO has hit a record low, unilateralism and protectionism have risen, and uncertainties and unstable factors have increased significantly. The situation facing China’s foreign trade development is still severe and complicated. "

　　Gao Feng introduced that in the next step, the Ministry of Commerce will closely focus on the objectives and tasks of promoting stability and improving quality of foreign trade throughout the year, pay close attention to the implementation of stable foreign trade policies, and ensure that relevant policies benefit market players as soon as possible. "Accelerate the cultivation of new foreign trade formats and new models, guide the gradient transfer of processing trade and stabilize the development of processing trade. Actively promote the innovative development of border trade. Speeding up import trade and promoting the construction of innovation demonstration zone. Support export products to domestic sales. Continue to improve the level of trade facilitation. "

　　As a "barometer" of China’s foreign trade, the 128th China Import and Export Fair, the Canton Fair, will be held online from October 15th to 24th, with an extension of 10 days.

　　In recent years, with the rapid development and wide application of digital technology, digital economy and trade have flourished and become the highlight of economic development and international economic and trade cooperation in various countries. Data show that in 2019, the added value of China’s digital economy reached 35.8 trillion yuan, accounting for 36.2% of GDP. At the just-concluded 2020 Service Trade Fair, many places and departments have also put forward relevant layout plans to accelerate the development of digital trade.

　　Gao Feng introduced that since the beginning of this year, the Ministry of Commerce, together with the Central Network Information Office, the Ministry of Industry and Information Technology and other departments, has studied the framework of digital trade system, put forward a digital trade work plan, and selected the first batch of 12 digital service export bases based on comprehensive evaluation, supported and guided these bases to try first, and promoted the improvement of digital trade policies and systems in the practice of digital trade.

　　"In the next step, the Ministry of Commerce, together with the Central Network Information Office and other departments, will continue to push forward the pilot work of comprehensively deepening the innovation and development of service trade, regard digital trade as an important part of the new round of pilot projects, guide relevant pilot areas to actively explore, continuously optimize the allocation of digital resources, and stimulate the development potential of China’s digital economy and trade." Gao Feng said.

[Network+] China basketball finally won the first world championship in adult competition! In the women’s final of the 2019 FIBA Three-Man Basketball World Cup held in the early morning of 24th, the China women’s team beat the Hungarian team, a European powerhouse, by 19:13 to win the championship. Last night’s "News Network" broadcast this good news.

When it comes to basketball games, the first thing we usually think of is 5X5, that is, five players from each side will play in four sessions with 10 minutes each (12 minutes for NBA and CBA). The public is much more unfamiliar with three-person basketball, and more may only stay in "knowing" that there is a KFC national youth three-person basketball championship challenge that has been held for 15 years in a row. Today, Lianjun will tell you about the "past life" of this sport.

Indeed, compared with the history of more than 100 years of five-a-side basketball competition, the popularity and popularity of three-a-side basketball, which was first played in world-class competition in 1992, is indeed much inferior. However, because it does not need much space (half of the five-person system), the single game time is short (10-16 minutes per game), and it is more suitable for training beginners’ technical movements and technical and tactical cooperation, it is very popular among young students.

In recent years, 3X3 basketball has made more and more appearances in the world. The FIBA Three-Man Basketball World Cup, which was won by the China women’s team, has been held for six times since it was first held in 2012. In 2017, the International Olympic Committee officially added the three-person basketball game to the Olympic Games.

After winning the World Cup, the China women’s team also successfully won the Olympic tickets, and we will see them again at the Tokyo Olympic Games next year.

"Many skills of three-person basketball and five-person basketball are the same. Whoever can put more balls into the basket will win." David Crocker, executive director of FIBA, once explained this sport. However, the difference between skills and actual combat also makes them have their own characteristics. From some angles, they can also be two completely different sports.

Only three players are present, which means it is difficult to distinguish the roles of "striker" and "defender", so everyone should get used to playing the role of generalist. The shrinking of the venue makes the confrontation more intense and the play faster. It is enough for each team to have four good players when three people play. Compared with the five-a-side basketball game, each team needs 8-12 excellent players to attack the medals. This game is undoubtedly more suspenseful, and anyone can become a winner.

Such suspense also makes it more possible for China to play three-person basketball in the future.

In the field of five-a-side basketball, China can’t be called a traditional strong team. Previously, China’s best performance in the world was the runner-up of the women’s team at the 1992 Barcelona Olympic Games. Although the men’s basketball team won the eighth place in four Olympic Games, it is always difficult to take a step forward.

But the situation is much better in three-person basketball. If you count the youth competitions, China won the championship as early as 2010. In the first World Youth Olympic Games, China U17 women’s three-person basketball team beat all the strong teams and finally won the gold medal. At last year’s Asian Games in Jakarta, the men’s and women’s teams of China swept the championship in this event. This makes us have more expectations for next year’s Olympic Games.

It is worth mentioning that, due to the good mass foundation, the three-person basketball game has more advantages in talent selection than the five-person basketball game, which also lays an excellent foundation for the future development of this project.

The four players of the men’s basketball team that won the championship in the Asian Games last year can be called "grassroots": Huang Wenwei, who scored the winner in the final, is a teacher of Guangzhou Institute of Physical Education, xiao hailiang is an employee of Dongguan Cultural and Sports Bureau, Zeng Bingqiang is a student of Guangdong University of Technology, and Chen Gong is from Hubei team, but so far, he has not played in the professional league. And they were able to get on the stage of the competition, all through the "I want to go to the Olympics" three-person basketball competition held in chinese basketball association at the beginning of last year.

After the two words "all the people" and "Olympic Games" are closely linked, China three-person basketball will surely enter a better era.

　　This report is compiled in accordance with Article 50 of the Regulations of People’s Republic of China (PRC) Municipality on the Openness of Government Information (hereinafter referred to as the Regulations on the Openness of Government Information).

　　I. General situation

　　In 2021, the Changping District Government earnestly implemented the Regulations on the Openness of Government Information, continuously expanded the open content, innovated the open forms, improved the open system, strengthened the open supervision, and promoted the open work of government information and government affairs in an orderly manner.

　　(A) the implementation of open process specification

　　The first is to compile the "Changping District Government Information and Government Affairs Disclosure Work System Manual", refine nine system rules, and standardize the government affairs disclosure work process in the whole region. The second is to strengthen the voluntary disclosure of government information, standardize the setting of government information disclosure columns, and timely release the statutory voluntary disclosure content. Special topics such as "the construction of two districts" were established, and information in key areas such as the approval and implementation of major construction projects, the allocation of public resources, people’s livelihood, law enforcement supervision, and urban and rural construction was actively disclosed, and 3,401 pieces of information were released throughout the year. The third is to optimize the mechanism of disclosure according to the application, and actively respond to the needs of enterprises for government information disclosure. The whole region has handled 923 applications for government information disclosure. The fourth is to strengthen the business guidance for the open work of all units, combine the online business training of the universality of government affairs disclosure with the offline analysis and discussion according to the application difficulties, and promote the continuous improvement of the standardization level of government information and government affairs disclosure in the whole region.

　　(2) Strengthen the management of open platforms.

　　First, strengthen the construction of the website platform of the district government and improve the application efficiency of data classification management of government websites. Strengthen the construction of information content on government websites to ensure timely information release and update. The second is to complete the development and testing of the "Pingping" function module of the government service intelligent robot and the development of WeChat applet, expand the knowledge base data by more than 14,000 pieces, realize the voice interaction function, and provide instant question and answer service for the enterprise masses. The third is to strengthen the application of cutting-edge monitoring and inspection technologies such as big data and cloud monitoring, refine the assessment rules for new government media, and implement the monthly notification system for government websites and new government media work.

　　(3) Improve the interaction mechanism between the government and the people

　　The first is to expand public participation in policy formulation. For policy documents concerning people’s interests and people’s livelihood, the function of "I want to make suggestions" is set to collect people’s opinions and give play to the role of public participation in the process of policy formulation. The second is to intensify the policy interpretation, and interpret 17 district-level policy documents in an easy-to-understand way, such as illustrated cases, policy questions and answers, videos, etc., so that enterprises can understand and understand them well. Third, we will actively carry out a series of activities of "I do practical things for the masses", hold four "policy public lectures" and 11 "government open days" around optimizing the business environment, improving people’s livelihood and safe production, strengthen the interactive communication between the government and the people, and guide the public to participate in social governance in an orderly manner.

　　(D) to strengthen the assessment and supervision.

　　Incorporate government information and government affairs disclosure into the performance appraisal scope of the district government, and further optimize the appraisal rules. Carry out third-party evaluation of government information and government affairs disclosure on a quarterly basis, and report the evaluation results. There was no accountability in the whole year.

　　Second, the initiative to disclose government information

　　Iii. Receiving and handling applications for government information disclosure

　　Four, the government information disclosure of administrative reconsideration and administrative litigation.

　　V. Main Problems and Improvements

　　The main problems are as follows: First, the disclosure of government information by various units lacks depth and breadth, and the disclosure ratio of government information concerned by enterprises and the masses is not high. Second, the underlying content management platform system of government websites cannot fully meet the requirements of intelligent and digital applications of government websites. The operation and maintenance management of new government media is not standardized. Third, the staff’s professional ability needs to be improved, and the work norms and standards need to be further strengthened.

　　Improvement: First, we will promote the integrated development of government information, government affairs disclosure and government affairs service, combine the disclosure of statutory contents of government information with the disclosure of information needed for handling affairs, and promote the whole process of handling services to fully meet the personalized service needs of handlers. The second is to continuously upgrade and explore the in-depth application of new technologies in the government information disclosure platform, and promote the integrated development of government websites and government new media knowledge bases. The third is to establish a normalization mechanism for government information and government affairs publicity training, form good measures into typical cases, adopt video, offline meetings and other forms of experience exchange, earnestly do a good job in business guidance, and improve the business ability of government information and government affairs publicity staff in all units in the region.

　　Vi. Other matters that need to be reported

　　This unit collects information processing fees according to the Measures for the Administration of Information Processing Fees for Government Information Disclosure. In 2021, there were 0 pieces of charge notices, with a total amount of 0 yuan. The total amount actually collected is 0 yuan.

Xi ‘an Jansen became history, Novartis spun off Sandoz, Pfizer Vaccine Division changed coaches, and Abbey’s position as the "king of medicine" was not guaranteed … Since September, many multinational pharmaceutical companies have experienced great changes from personnel to department structure to R&D pipeline.

Over the years, Greater China has been an important market component of many multinational pharmaceutical companies, and it is also the main driving force for their performance contribution. In the post-epidemic period, factors such as the difficulty in research and development of innovative drugs, declining performance, fierce competition in the same industry and continuous changes in industry policies are all affecting the strategic adjustment and personnel changes of multinational pharmaceutical companies in China. How to go in the second half of 2023? These pharmaceutical companies have taken the lead in making adjustments.

Johnson & Johnson: The History of Xi ‘an Janssen

The brand rejuvenation of the former giant Johnson & Johnson attracted the most attention. On September 14th, Johnson & Johnson announced that it would integrate its medical technology and pharmaceutical businesses into Johnson & Johnson’s name. Among them, Jansen changed its name to Johnson & Johnson Innovative Pharmaceutical, which also means that the logo of "Xi ‘an Jansen" will become history.

Once upon a time, the advertisement of Xi ‘an Jansen, "Stomach power is insufficient, please help with motilium", went deep into thousands of families in China, so that its Dakening, Sismin, Caile, Tylenol … all became necessities at home. The history of Xi ‘an Jansen dates back to 1961, when the Belgian scientist Dr. Paul Jansen joined Johnson & Johnson with his Janssen Pharmaceutical Companies. Since then, the strength of the Johnson & Johnson pharmaceutical sector has been greatly enhanced, and the research and development of prescription drugs has also been on the right track. However, after 2002, the OTC products that Xi ‘an Jansen relied on for a living began to decline. The fundamental reason was that the original star products, Motilium and Dyclonine, were already in the decline period of product life cycle, and the follow-up new products were unsustainable. Johnson & Johnson Group never gave Xi ‘an Jansen any new product support.

In 2021, under the pressure of cost, Johnson & Johnson began to carry out drastic reforms, divesting the consumer health business and listing it independently, becoming a dual-business company spanning the two major sectors of medical equipment and medicine. This series of reforms has also kept its performance growing in recent years. The semi-annual report in 2023 showed that its total revenue exceeded the $50 billion mark, among which the revenue of pharmaceutical business in the first half of the year increased by 3.7% year-on-year to $27.144 billion. Immunity and tumor were the main sources of performance in Johnson & Johnson’s pharmaceutical business.

In the future, Johnson & Johnson will focus more on the fields of tumor, immunity, nerve, cardiovascular, pulmonary hypertension and retina, and develop cutting-edge drugs. In terms of personnel structure, Joseph Wolk, chief financial officer of Johnson & Johnson, said last year that due to economic pressure and the separation plan of consumer health business, Johnson & Johnson may moderately reduce the number of employees.

Pfizer: structural adjustment

Since September, the structure of Pfizer China’s Hospital Emergency Division and Vaccine Division, as well as the changes of relevant responsible persons, have come into effect. Among them, the head of the Vaccine Division changed from Zhang Lingyan to Yang Bei, and there are North China District, South China District and Market Platform under the charge of Hao Yikai, Shi Yinli and Jin Xinqing respectively. It is understood that although Yang Bei is the new leader of the Vaccine Division, she has been working in Pfizer for 25 years, and the other three responsible persons have been in Pfizer for more than ten years.

Some insiders speculate that the coaching change of Pfizer Vaccine Division may be related to the performance pressure of its vaccine products. According to Pfizer’s forecast, the revenue of its two major COVID-19 products, vaccine (Comirnaty) and oral medicine (Paxlovid), will be about $13.5 billion and $8 billion in 2023, respectively, down by 64% and 58% compared with 2022, and the gross profit of COVID-19 vaccine will be equally divided with BioNTech.

At the same time, another star product of Pfizer, 13-price pneumonia vaccine Pei Er 13, successfully expanded its age in April this year, but with the catch-up of domestic pharmaceutical companies, Pei Er 13 is no longer the only choice in the China market. In 2020 and 2021, watson biological’s Woanxin and Minhai Bio’s Weimin Feibao were listed successively, and the prices were 598 yuan/dose and 458 yuan/dose respectively, which were significantly lower than Pei Er’s 698 yuan/dose. And as early as before Pei Er’s 13th birthday, the vaccination targets of Woanxin and Weimin Feibao were infants and children from 6 weeks to 5 years old (before the 6th birthday).

However, judging from the coaching change, Pfizer remains optimistic about the vaccine field and the China market. According to the data of the semi-annual report, Pfizer increased the cost of vaccine product research and development by 530 million US dollars in the first half of this year. As of June this year, Pfizer has 12 vaccines under research, and 1/3 of them have entered Phase III clinical practice.

Lilly: preparing for diet pills

On October 1st, Yuan Ping, the current acting head of Lilly’s Diabetes Alliance Division, was appointed as the national executive sales director of Diabetes Portfolio Division, and the head of Diabetes Alliance Division was replaced by Liu Aihua, the current head of Cancer Portfolio Division. This change may be a warm-up for the launch and promotion of the slimming and hypoglycemic drug telpotide in the second half of this year.

The semi-annual report shows that Lilly’s total revenue in the first half of the year was 15.272 billion US dollars, up about 7% year-on-year; The net profit was US$ 3.108 billion, up about 9% year-on-year, of which Telpotide achieved sales of US$ 980 million. Not only has the performance increased significantly, but under the expectation of diet pills and new drugs for Alzheimer’s disease, as of September 25th, Lilly’s total market value has reached as high as $524.3 billion, with a share price of $522. Telpotide, like Novo Nordisk’s Smegrupeptide and Liraglutide, belongs to the most popular GLP-1 drugs at present. The indications for weight loss of Lilly Telpotide injection were declared and listed in China in August, and it is expected to be listed at the end of the year.

Abbey: Looking for the Next "King of Medicine"

Recently, AbbVie terminated two agreements with innovative pharmaceutical companies in China. Tianjing Bio announced on September 22nd that AbbVie had terminated the agreement with lemzoparlimab, a candidate drug for CD47 antibody jointly developed and sold by the company in 2020, and the termination agreement will take effect on November 20th this year. It is understood that CD47 is another hot target after PD-1. Another project that was terminated was an authorized cooperation between AbbVie and Jiakesi Pharmaceutical, a domestic biopharmaceutical company, on SHP2 inhibitors. Garcos announced the termination of the project in July this year, and within 180 days of handover, AbbVie will continue to reimburse all expenses under the pre-approved development plan.

Many people were surprised by AbbVie’s decision to give up two innovative drugs from China. Some insiders speculate that it is because clinical trials have not reached expectations. In order to save costs, it is reasonable for AbbVie to give up these two projects.

In the past 20 years, Hummel, the "drug king", has brought more than $200 billion in revenue to AbbVie. However, at the beginning of this year, Amjevita, the first bio-similar drug of Hummel, officially entered the American market. In addition, nine bio-similar drugs competed with Hummel, resulting in a decline in its sales. In the first quarter of this year, AbbVie’s revenue was US$ 12.225 billion, down over 8% year-on-year, while Hummel’s revenue was US$ 3.541 billion, down over 20% year-on-year. AbbVie previously predicted that the franchise of Hummel will be eroded by about 45% in 2023, and AbbVie, who is eager to find the next "drug king", has been forced to terminate the research and development of seven ADC drugs.

Roche: Layout "New Troika"

Chen Shaofeng, the head of Roche’s specialty medicine field (ophthalmology, neuroscience, anti-infection and immunity) in China, resigned at the end of July. Since August 31st, Chen Kaijuan, the head of global integration strategy of Sufuda in Roche headquarters, has taken over the position of head of specialty medicine field, reporting directly to Bian Xin, president of Roche China.

Since last year, Roche has continuously optimized its strategic product portfolio in China. With the patent protection of "Troika" of Avastin, Herceptin and Rituximab expiring one after another, Roche is laying out a new "Troika", that is, expanding from a single tumor field to three major fields of "tumor, neuroscience and ophthalmology".

To this end, Roche has announced an additional investment of nearly 250 million yuan in China as working capital. Including this investment, Roche has invested a total of 1.4 billion yuan in the China market in three years. At present, Roche’s investment has achieved initial results. According to the data of the semi-annual report, Roche’s total business income was 22.681 billion Swiss francs (about 181.624 billion yuan), an increase of 8% year-on-year; Among them, the pharmaceutical business income in China was 1.505 billion Swiss francs (about RMB 12.052 billion), up 3% year-on-year, accounting for 6.6% of Roche’s global pharmaceutical business income.

Sanofi: Stick to the "Slimming Plan"

On August 31st, Sanofi, a French pharmaceutical giant, announced that Bill Hibbard, the head of its global specialty drugs, had resigned. On September 18th, Sanofi sold its 11 central nervous system products to Pharmanovia, another multinational pharmaceutical company.

In the past two years, Sanofi has been actively "slimming" by selling consumer health care brands and 17 drugs in the fields of central nervous system diseases and vascular diseases. This series of "sale plans" has been advocated by Paul Hudson, the current CEO of Sanofi, since he took office. In 2019, he put forward the "play to win" plan, aiming to focus Sanofi’s business on key research and development fields such as immune inflammation, rare diseases, tumors and vaccines from 2020 to 2025.

At present, the slimming plan has not changed. As of the first half of this year, Sanofi has at least 78 clinical projects, most of which are concentrated in the above key areas. According to the semi-annual report, Sanofi’s sales in the first half of this year reached 20.187 billion euros (about 156.389 billion yuan), a year-on-year increase of 2%. Among them, the core product, that is, Duplex monoclonal antibody in the self-exemption field, sold 4.878 billion euros (about 37.77 billion yuan). Two new drugs approved last year: Enjaymo, which is used to reduce the demand for red blood cell transfusion caused by hemolysis in adults with cold agglutinin’s disease (CAD), and Xenpozyme, which is used in children and adult patients with acid sphingomyelinase deficiency (ASMD), have achieved an increase in volume, with an increase of 1800% and 750% respectively in the first half of the year. It can be seen that after getting rid of the non-main business, Sanofi has played a "home court advantage" more easily.

Novartis: Spinning off Generic Drug Subsidiary

On September 15th, Novartis announced that on October 4th, Sandoz, a subsidiary of Novartis, which specializes in generic drugs and bio-similar drugs, was officially split.

It took Novartis nearly five years to divest Sandoz. The initial split news came out in 2018, when Sandoz’s performance showed a downward trend and dragged down Novartis. Although Sandoz, Tiwa and Huizhi dominate the world’s top three in the field of generic drugs, Sandoz’s generic drugs brought Novartis only one-fifth of the total revenue in 2022, and the rest were created by innovative drugs. The data shows that in 2022, the revenue of Novartis innovative drugs was 41.296 billion US dollars, accounting for 82% of its total revenue; Sandoz’s revenue is $9.249 billion.

In order to become a truly innovative drug company, Novartis has been split up in recent years. In addition to Sandoz, Novartis also split Alcon, one of the largest ophthalmic products and equipment companies. In addition, in the field of treatment, Novartis has also focused on cardiovascular, kidney and metabolism, immunity, neuroscience and tumor from more than 10 original concerns.

At present, Novartis is moving towards the goal of being the largest innovative pharmaceutical company in the world. In the first half of this year, Novartis’s net sales were US$ 26.575 billion (about RMB 194.314 billion), a year-on-year increase of 5%; The net profit was US$ 4.611 billion (about RMB 33.715 billion), a year-on-year increase of 32%.

Immena: poor performance for "veteran"

Inmina, the leader in gene sequencing, announced on September 20th that Li Qing, the company’s global senior vice president and general manager of Greater China, had left. The day before, Waters announced the appointment of Li Qing as the company’s vice president and general manager of Greater China.

Imina is a global leader in gene sequencing and chip technology, and its product line covers scientific analysis instruments such as sequencing platforms, chip scanners and in-vitro diagnostic sequencers. But in recent years, the performance in China market is not good. In the fourth quarter of 2022, the revenue of Mina China dropped by 22%, and in the first quarter of 2023, the revenue dropped by 28% to 91 million US dollars (about 665 million yuan). According to this year’s semi-annual report, in the second quarter, Mina’s performance in China was still declining, and its revenue was US$ 115 million (about RMB 841 million), down 3% year-on-year.

In this regard, Immena explained that global inflation, exchange rate, slowing economic growth, and market competition have caused poor performance. Now that "veteran" Li Qing has gone, the challenge is still there, because it is still unknown whether Mina’s performance will pick up in the second half of the year.

GSK: R&D has been frustrated repeatedly

Recently, GSK announced that Dr. John Lepore, Senior Vice President and Director of R&D, had left the company. Dr. Kaivan Khavandi, the new R&D director who will succeed him, will lead GSK’s restructured respiratory and immunology department. On September 11th, WestlyYu, the current vice president of GSK China and head of respiratory business, was appointed as vice president and head of special medicine business, and continued to be one of the leading teams of GSK China, reporting directly to Qi Xin, general manager of GSK China. There are indications that the GSK changes not only personnel, but also internal structure and research and development direction.

In recent years, GSK has had a hard time, especially in the research and development of new drugs with high investment and high risk. In November 2022, an ADC drug under GSK was stopped by the FDA; In February of this year, the CEO of GSK announced that he would end all investment in gene therapy; In addition, GSK’s PD-1 drug Jemperli, which was acquired by acquiring Tesaro for $5.1 billion, sold only $8 million in the first half of 2022, far below GSK’s expectations.

GSK’s executive adjustment may be to change the status quo of making ends meet. GSK divides the R&D department into three groups: respiratory and immunology, vaccines and infectious diseases, and oncology, which are dedicated to initial discovery and early clinical research. GSK also said that it will not reduce investment in research and development, and will accelerate the development of products in the future.

AstraZeneca: Increase investment in China.

According to the British "Daily Mail" reported on September 10th, the CEO of AstraZeneca may leave as soon as next year. Although changes are on the way, AstraZeneca’s development in China is becoming more and more "localized". In 2023, AstraZeneca celebrated its 30th anniversary in China. Over the past 30 years, the China market has become increasingly important in AstraZeneca’s global strategic position, with R&D investment in China reaching 1.5 billion US dollars and investment exceeding 1 billion US dollars. At present, China has developed into AstraZeneca’s second largest market in the world, and is gradually changing from the original "main sales place" to "main production place" and "main creation place".

Following the formal signing of the domestic production and supply base of Budigefu inhalation aerosol with a total investment of about 450 million US dollars with Qingdao High-tech Zone on March 25th this year, AstraZeneca planned to invest another 250 million US dollars in Qingdao inhalation aerosol production and supply base project on August 14th, in order to increase the canning production capacity and build an inhalation aerosol packaging production line, and further expand the production and supply base capacity. In addition, it is reported that AstraZeneca will also set up a research and development center in Hong Kong.

Bayer and Bojian: A wave of layoffs is coming.

On September 15th, it was reported in Reuters that Bill Anderson, CEO of Bayer, was considering cutting management, and the specific plan will be put forward at the recent internal strategy meeting. On the same day, Oliver Kohlhaas, head of Bayer strategy, announced his resignation.

Although Bayer’s global spokesman declined to comment, Bayer’s layoffs have already begun. In February of this year, Bayer launched the "Resignation Option Plan" in California, USA, which laid off 55 employees who were over 55 years old and had served for 10 years. In August, BlueRock Therapeutics, a cell therapy company owned by Bayer, announced that it would lay off about 50 employees. In addition, since 2023, Bayer’s share price has only increased by 6%, far less than its peers, and Novartis’s share price has increased by 18% in the same period. It is reported that in the next few months, Bayer will formulate a more official comprehensive restructuring plan to boost the company’s share price, and many investors hope that it can split the two major departments of agriculture and medicine and go public independently.

Bayer is not the only one to reduce costs and increase efficiency. In July, Bojian, who just made a major breakthrough in the field of drugs for Alzheimer’s Harmo, announced that it would try to save $1 billion in operating expenses by 2025 by laying off 1,000 people and stopping the research and development of at least four drugs, and spend $300 million of it on the research and development of new drugs.

Survival, operational efficiency and clinical demand have always been the three driving forces for the continuous reform of domestic and foreign pharmaceutical companies. The reform and adjustment of multinational pharmaceutical companies are also inseparable from these three factors. In addition, in the face of a more complex and huge China market, it will take more effort. How innovative drugs can enter medical insurance, how to promote them after entering medical insurance, and how to compete with similar products have forced multinational pharmaceutical companies to make constant adjustments in structural changes, internal resources and key teams.

At present, the policy that has the greatest impact on the performance of pharmaceutical companies in the second half of the year is undoubtedly the medical anti-corruption action that is expected to last for one year. Tang Aijin, chief analyst of Cinda Securities Medicine, believes that medical anti-corruption will affect the sales rhythm in the short term, but it will not be broken. Strengthening the restriction and supervision of the whole industry will benefit the long-term healthy development of the industry, and pharmaceutical companies will pay more attention to R&D and innovation after the sales expenses are limited.

Camp of Wu ‘a Highway Project Department of China Hydropower Company. On January 28th, the project department was attacked by Sudanese rebels, and 29 China workers were kidnapped. Information photo This version of the picture is based on the website of China Hydropower Corporation.

Asphalt pavement construction of Sudan Wu ‘a highway. Information photo

　　29 kidnapped Sudanese workers are still under the control of anti-government forces and are in South China; The whereabouts of one abductee is unknown.

　　■ "The Chinese enterprise Sudan was attacked and more than 20 Chinese were missing" tracking.

　　Comprehensive Xinhua News Agency The Embassy of China in Sudan confirmed on the 30th that 17 China workers of China Company who were attacked a few days ago have been transferred to a safe place by Sudanese government forces.

　　In addition, 29 previously kidnapped China workers are still under the control of Sudanese rebels.

　　A total of 29 China workers were abducted.

　　A person in charge of China’s embassy in Sudan told Xinhua News Agency that China Hydropower Corporation was attacked by the anti-government armed forces "Sudan People’s Liberation Movement" (Northern Bureau) at a highway project site in South Kordofan, Sudan, and 29 China workers were kidnapped. Other personnel in the construction site scattered and hid near the construction site in time. Sudanese government forces then found 17 China workers and moved them to a safe place.

　　At present, the Embassy of China in Sudan and other relevant departments in China are continuing to communicate with the Sudanese side and actively rescue the 29 China workers who were abducted.

　　The embassy sent a working group to assist in the rescue.

　　China’s embassy in Sudan said on the 30th that it had sent a four-member working group to help the Sudanese government rescue 29 China workers who were abducted by local rebels.

　　An embassy official said that a working group consisting of three diplomats, including the Political Counselor, and a person in charge of China Hydropower Corporation went to Bailly, the capital of North Kordofan State, to meet 17 China workers who were safely transferred by Sudanese government forces. Subsequently, the working group will participate in helping to rescue the hijacked workers in China.

　　An official of China’s embassy in Sudan said that all communications between the kidnapped China people and the outside world were cut off. South Kordofan, where the attack occurred, borders South Sudan and is one of the most rampant areas of anti-government armed activities. Anti-government forces are mainly entrenched in the Nuba Mountains in the state.

　　There are 47 China workers on the construction site.

　　On the 28th, a highway project site of China Hydropower Corporation in South Kordofan, Sudan was attacked by the anti-government armed forces "Sudan People’s Liberation Movement" (Northern Bureau).

　　At the time of the incident, there were 47 China workers in the construction site, 29 of whom were abducted by anti-government forces, and the other 18 workers scattered and hid near the construction site in time. The Sudanese government forces then found 17 China workers who were not abducted and moved them to a safe place, but the whereabouts of one China worker are still unknown, and the Sudanese government forces are continuing to search for his whereabouts.

　　An official of China’s embassy in Sudan said that 29 kidnapped China workers are still under the control of anti-government forces.

　　■ reaction

　　The Ministry of Commerce issued a security reminder.

　　The Ministry of Commerce issued a message yesterday, reminding China’s relevant enterprises and personnel in Sudan to do a good job in safety precautions, pay close attention to the changes in the local security situation and ensure the safety of life and property.

　　"There is no problem in the capital." Mr. Liu, an employee of China Hydropower Company who works in Khartoum, said that the situation in Khartoum, the capital of Sudan, is relatively safe and life has not had much impact. The Embassy and the Commercial Counsellor’s Office require Chinese companies in the Soviet Union to be vigilant and take various measures to ensure safety.

　　According to Mr. Liu, in Sudan, Chinese specially grows vegetables from China and supplies them to Chinese-funded units. South Kordofan, Sudan, which was attacked on the construction site in China, is located on the border between North and South Sudan. Usually, the living conditions of workers are quite good, and the company has uniform accommodation standards. Like Khartoum, the food we eat is also grown in Chinese and then delivered.

　　According to a senior official of a state-owned investment enterprise who once lived in Sudan, both state-owned enterprises and private enterprises in China have many projects in Sudan. In the area north of Khartoum, because of the low population density, the people are very comfortable and the social order is good, but there is always a conflict between herders and aborigines at the junction of the south and the north. According to its introduction, most of the state-owned projects are in the north, but they are gradually going to the south. The hydropower highway project in this accident belongs to the famous "Six Roads and One Bridge" project in South Kordofan, where there are many conflicts.

　　■ statement

　　"Beifangju or pressure the government by kidnapping"

　　In response to the hijacking incident, the reporter interviewed He Wenping, a researcher at the African Institute of the Chinese Academy of Social Sciences. He Wenping pointed out that this is a rare large-scale kidnapping of China workers in recent years. She thinks that the kidnapping is unlikely to be aimed at China workers, possibly for financial purposes, and it is unlikely to have much impact on China’s investment in Sudan.

　　Since the Northern Bureau has not indicated the purpose of kidnapping China workers so far, He Wenping analyzed two possibilities. First, it was politically motivated. Because of its anti-government armed nature, the Northern Bureau may have pressured the government by kidnapping China workers, so as to get the government to agree to some of their demands; The second possibility is the purpose of money, that is, kidnapping for ransom He Wenping also pointed out that because the kidnapping place is the focus of the conflict between the Northern Bureau and the government forces, it does not rule out the possibility that the Northern Bureau did not plan it, but just stole the China workers.

　　He Wenping pointed out that the hijacking incident raised a new problem for China’s overseas investment, that is, how to consider the security cost of outsourced projects, such as the construction of projects in a complicated country like Sudan, and the risk level naturally increased. He Wenping pointed out that although unstable factors increase the cost of engineering safety, certain strategies can be adopted to balance risks. For example, assess and investigate the risk areas in Africa, classify the risk levels, and observe the changes of local risk levels at any time.

　　■ progress

　　"Some robbed China workers were rescued" is not true.

　　On the 30th, members of the Sudanese delegation attending the 18th African Union Summit in Addis Ababa denied reports that 29 China workers kidnapped in Sudan had been partially rescued.

　　The member of the Sudanese delegation, who asked not to be named, said that 29 Sudanese workers kidnapped in the border area between Sudan and South Sudan are currently in South China, and the report that some of the kidnapped workers were rescued is not true. He said that the Sudanese side kept close contact with the kidnappers and would do everything possible to rescue the workers in China.

　　Earlier, foreign news reported that Sudanese government forces successfully rescued 14 China workers abducted by anti-government forces on the 30th. Our reporter connected Liu Zhenyong, spokesmen of the China Embassy in Sudan, and told reporters that the Sudanese military rescued 17 workers from China. These 17 workers were not the 29 abducted China workers, but other workers hiding near the Chinese camp. These people were not injured. For safety reasons, Liu Zhenyong said that the details of the rescue and the location of the rescued workers could not be disclosed.

　　He said that at present, the embassy is closely carrying out search and rescue work, actively contacting relevant Sudanese departments, and will disclose the progress to the outside world in a timely manner, but can not disclose specific details for the time being.

　　Armed groups promised to release China workers.

　　In the early morning of January 30th, Beijing time, Yasser arman, secretary general of Sudan People’s Liberation Movement (Northern Bureau), an anti-government armed force in Sudan, said in an interview with CNTV reporter that Sudan People’s Liberation Movement (Northern Bureau) would never oppose China and Chinese, and guarantee the safety of China workers and release them.

　　Arman also said: "We are a force for peace, stability and global coexistence. The leadership of Sudan People’s Liberation Movement (Northern Bureau) and myself — — The Secretary-General and Chairman are doing their best to get accurate information about Chinese’s detention from our troops at the front line in South Kordofan. If China citizens are with the army of the Sudan People’s Liberation Movement (Northern Bureau), please rest assured that we will ensure their safety and release them. "

　　■ The kidnapping of China workers in Sudan.

　　On October 3, 2011, a PetroChina worker was killed by unidentified gunmen in South Kordofan, Sudan, and another was injured.

　　On October 18, 2008, nine employees of PetroChina were kidnapped by local rebel militants at a construction site in southwest Sudan, five of them were killed and four were rescued.

　　On March 26th, 2004, two China workers were killed by mobs in Sudan. They were pilots of Sudan Project Department of Liaohe Oilfield Road Construction Company under China Petroleum and Natural Gas Group Corporation.

　　This version of the manuscript (except signature) is integrated with CCTV.

　　Our reporter Danielle Courbe Chu Xinyan Jin Yu Shen Yuqing and other reports.