In order to thoroughly implement the spirit of the 20th National Congress of the Communist Party of China, solidly promote the implementation of the Outline of Building a Powerful Traffic Country, the Outline of the National Comprehensive Three-dimensional Traffic Network Planning and the Outline of the Comprehensive Three-dimensional Traffic Network Planning of Anhui Province, fully link up the National Highway Network Planning, optimize and improve the ordinary provincial highway network, strongly support the construction of a strong traffic province, and strive to be a pioneer in the construction of a modern and beautiful Anhui Province. The planning period is up to.In 2035.

　　First, the foundation of development

(1) Implementation of the last round of planning

The general provincial highway network planning in Anhui province (2016 -2030) It is clear that the total size of provincial highways in ordinary countries is about 23,320 kilometers, of which the ordinary national highway consists of 3 capital radial lines, 7 north-south longitudinal lines, 12 east-west transverse lines and 2 connecting lines, with a mileage of 7,641 kilometers; Ordinary provincial roads are composed of 5 radial lines, 55 north-south longitudinal lines, 49 east-west transverse lines, 95 tie lines (including 15 long-term prospect lines) and 6 loop lines, with a mileage of 15,679 kilometers. Since the promulgation and implementation of the plan, it has effectively guided the construction of ordinary national and provincial highways in the province. The trunk highway network has been continuously improved and the technical level has been steadily improved, which has played an important role in promoting economic and social development and optimizing industrial layout.byBy the end of 2022, the total mileage of ordinary national highways in our province was 23,382 kilometers, and the road network density was 16.7 kilometers/100 square kilometers, including 15,876 kilometers of ordinary provincial highways (including 416 kilometers of built prospect lines) and 8,550 kilometers of second-class and above sections, accounting for 53.9%.

Standing at a new historical starting point, facing the new situation of building a modern economic system and a socialist modern power in an all-round way, and the proposal of the provincial party Committee and government to buildWith the new requirements of "three places and one district" and building "seven strong provinces", the common national and provincial highways still need to be strengthened in terms of inter-provincial interconnection, efficient access to cities and counties, coverage of important economic nodes, river-crossing development and integration with other modes of transportation, and the quality and efficiency of development need to be further improved.

(2) The situation requires

At present, our province is in a critical period of rising period, with strong kinetic energy and great potential. The development opportunities and challenges are facing new changes. The superposition of national strategies, scientific and technological revolution and industrial transformation, and the acceleration of service to build a new development pattern have put forward new and higher requirements for ordinary provincial roads to better play their leading and basic guarantee roles.

1.Serving the implementation of major national strategies requires ordinary provincial roads to further improve the level of interconnection..With the integration of the Yangtze River Delta, the development of the Yangtze River Economic Belt and the central regionriseWith the in-depth implementation of the national strategy, the development process of regional integration has been accelerating. As the foundation and main skeleton of the province’s comprehensive three-dimensional traffic network, ordinary provincial roads should be further improved.andThe level of connectivity of neighboring provinces, close regional spatial ties, and promote regional economic and social integration with transportation integration.

2.Service accelerates the construction of a new development pattern, which requires ordinary provincial roads to continuously improve the coverage level of important nodes..The Sixth Plenary Session of the Eleventh Provincial Party Committee stressed that it is necessary to actively serve and integrate into the new development pattern and firmly grasp the creation.The strategic positioning of "three places and one district" will accelerate the construction of "seven strong provinces" and strive to promote the high-quality development of the province to achieve new breakthroughs. As an important infrastructure connecting the central cities and major economic zones in the province, ordinary provincial roads should focus on strengthening the coverage of important economic nodes such as towns and tourist attractions, and effectively promote the orderly and efficient flow of factor resources.Meet that need of stable and smooth supply chain of industrial chain,Support Anhui to better integrate into the national unified market and smooth the domestic and international double cycle.

3.Improving the overall efficiency of the comprehensive three-dimensional transportation network requires the strengthening of ordinary provincial roads and the overall coordination of other modes of transportation..To build a modern and high-quality comprehensive three-dimensional traffic network, it is required that the ordinary provincial highway network should strengthen the overall coordination with other modes of transportation, strengthen the connection and conversion function with important port areas, high-speed railway station, airports and other transportation hubs, pay attention to the effective connection with urban traffic and other levels of highway networks, promote the optimization of transportation structure, and promote the overall efficiency of the comprehensive three-dimensional traffic network.

4.Promote the countryThe realization of the goal of "double carbon" requires ordinary provincial roads to pay more attention to the transformation of development mode..Achieving carbon neutrality in peak carbon dioxide emissions is an inherent requirement for fully implementing the new development concept, building a new development pattern and promoting high-quality development. It is also a major strategic decision made by the CPC Central Committee to coordinate the overall situation at home and abroad. Ordinary provincial highway networks should pay more attention to green and low-carbon development, pay attention to the development and protection of land space, and reduce energy consumption and carbon emissions in the whole life cycle; More emphasis on technological innovation and empowerment, focusing on the integration and development with new infrastructure and related industries.

five.To meet the people’s new needs for a better life, ordinary provincial roads are required to accelerate the pace of high-quality development..Urbanization levelThe continuous improvement of the industrial base and the acceleration of the modernization of the industrial chain have driven the steady growth of passenger and freight demand in the province.High quality, diversification and personalizationPassenger transportDemand is increasing,The rapid growth of freight demand with high added value and strong effectiveness requires ordinary provincial highways to speed up the improvement of road network layout, optimize road network structure, comprehensively improve service level, and provide strong support for high-quality economic and social development.

Second, the overall requirements

(A) the guiding ideology

Guided by Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era, we should thoroughly implement the spirit of the 20th Party Congress, conscientiously implement the important guiding spirit of the important speech of the General Secretary of the Supreme Leader on Anhui’s work and the requirements of the Fifth and Sixth Plenary Sessions of the Eleventh Provincial Party Committee, adhere to the people-centered principle, base ourselves on the new development stage, implement the new development concept completely, accurately and comprehensively, serve and integrate into the new development pattern, and firmly grasp the integration of the Yangtze River Delta, the development of the Yangtze River Economic Belt and the central region.riseDevelopment opportunities such as the superposition of national strategies, give full play to the location advantages along the Yangtze River and offshore, and focus on promoting high-quality development.“Excellent network, strong coverage, smooth connectivity and promotion of upgrading"As the focus, optimize and improve the general provincial highway network layout, and constantly improve the comprehensive transportation development level, for the comprehensive construction.Modernize Anhui, strive to write a Chinese-style modern Anhui chapter and be a pioneer.

(2) Planning principles

Leading first, leading moderately.Adhere to the strategic basis of expanding domestic demand,To meet the people’s travel.demandandeconomySocial development needsaskAs the starting point and the foothold,Coordinate fairness and efficiency, strengthen regional coordination, and give full play to the basic and leading role of ordinary provincial roads.Moderate leadPlan the scale and layout of ordinary provincial roads.

Focus on key points and supply accurately..Based on the new requirements of building a modern and beautiful Anhui in an all-round way, we will focus on supporting regional integration, covering important economic nodes, breaking through the bottleneck of crossing rivers and speeding upDevelopment priorities such as "integration into the group", precise efforts, expanding high-quality incremental supply, and achieving a higher level of dynamic balance between supply and demand.

Overall coordination and integration.Strengthen ordinary darts andExpressway, national highway, rural highway, water transportation, railway,aviation, urban roads, etc.Organic cohesion,Improve the efficiency and level of comprehensive transportation..Promote the co-construction and sharing of highway infrastructure, and promote deep integration with culture, tourism and industry along the route.Serve the economic development of transportation industry.

Innovative wisdom, green security.Pay attention to scientific and technological innovation and empowerment, apply modern information technologies such as the Internet and big data, promote the construction of smart roads, and improve highway safety and service support capabilities. Adhere to ecological priority, intensively use resources, reduce energy consumption and carbon emissions, and strive to build green roads to achieve harmonious development between roads and nature.

(3) Planning objectives

arrive2035In, the general national and provincial highway network with perfect network, reasonable layout, close connection and efficient operation was fully formed and basically realized."Fast inter-provincial access, efficient and smooth cities and counties, comprehensive coverage of township nodes, deep integration of important scenic spots, convenient communication of transportation hubs, effective relief of river bottlenecks, and obvious improvement of urban transit efficiency". The leading role of ordinary national and provincial highways in the development of national land space is increasingly prominent, the service function of industrial structure optimization is continuously improved, and the supporting role of economic and social development is continuously enhanced.

The network is more perfect.The common provincial highway and the common national highway together form a common trunk highway network that spans east and west, runs through north and south, covers the whole province and connects provinces. Form expressways and ordinary national and provincial highways throughout the province.“One master and one standby."Road network pattern, Anhui Province“fouraxisfiveporchsixThe main skeleton of the comprehensive three-dimensional traffic network with "corridor" basically forms "one main and many standby"“Double master and multiple standby"Road network pattern.

The layout is more reasonable.The distance between adjacent parallel roads of ordinary national and provincial roads is controlled in10Km or so, basically realized."National roads lead to counties and provincial roads lead to towns"; Inter-provincial exports continue to be encrypted, and the level of inter-provincial interconnection continues to improve; The network layout of key areas in the province is more optimized, and the cities and counties are efficient and smooth; The layout of river-crossing and Huai-crossing channels is more perfect, and the bottleneck of road network is effectively alleviated; Accelerate the construction of the tourism ring line, and further promote the integration of transportation and tourism; The urban transit plan is constantly optimized, and the development of roads and cities is more coordinated.

The connection is closer.realizeThe common national and provincial highways have developed in harmony with other modes of transportation, the function of connecting facilities has been continuously strengthened, the level of intensive integration and utilization of resources has been continuously improved, the connection of various modes of transportation has become more convenient and efficient, the collection and distribution system has been further improved, and the overall efficiency of comprehensive transportation has been effectively improved.

Run more efficiently.Basically realize all villages and towns,fourALevel and above scenic spots, provincial development zones and industrial parks and other important economic nodes.15Within minutes, you can go to ordinary national and provincial highways, important port areas, high-speed general interchange, high-speed railway station and other important transportation hubs.10Within minutes, you can go to the ordinary national and provincial roads, which strongly supports the construction of a modern economic system.

Third, the planning scheme

(A) the total scale

Plan toIn 2035, the total mileage of ordinary national highways in our province is about 26,205 kilometers, and the road network density is about 18.7 kilometers/100 square kilometers; Among them, the ordinary national highway is about 8300 kilometers, and the ordinary provincial highway is about 17905 kilometers.

1. Ordinary national highway

According to the National Highway Network Planning, there are common national highways in our province.29, the mileage is about8300 kilometers. The specific composition of the route is as follows:

table1 Anhui ordinary national highway planning route and mileage situation

2Ordinary provincial highway

Common provincial highwayThere are 249 lines, including 5 radial lines, 55 vertical lines, 48 horizontal lines, 131 tie lines and 10 loop lines, with a total mileage of 17,905 kilometers. See the annex for the specific route composition.

(2) Layout plan

oneOverall layout

The layout scheme of ordinary national roads has been clearly defined in the National Highway Network Planning, and the key points of this planning aresureLayout scheme and composition of ordinary provincial roads.

(1) Radiation, which is the connection line between Hefei and other cities in the province, has a total of 5 lines with a planned mileage of 1,143 kilometers, including Hefei.–Huaibei and Hefei–Fuyang and Hefei–Huangshan and Hefei–Xuancheng and Hefei–Maanshan.

(2) There are 55 longitudinal lines and north-south trunk highways.Total mileage6694Kilometers, such as East Union.-Huangshan, Miao ‘an-Zipeng, Xinxing-Banzhuyuan, etc.

(3) There are 48 horizontal lines and east-west trunk highways, with a planned total mileage.fifty-six48Kilometers, like a mound.-Yingdong, Cross-Madian, Huyang-Tiechong, etc.

(4) There are 131 connecting lines and provincial network lines, which mainly meet the needs of inter-provincial connection, node coverage and hub connectivity, with a planned total mileage.3929Kilometers, such as Suixi-Qiao Liu, Li Xing.–Linquan and Bowang-Yintang, etc.

(5) Ring road, with 10 lines depending on important tourist attractions, with a planned total mileage of 491km, including Chaohu Lake, Nvshan Lake, Wanfo Lake and Huannanyi.Lake, Taiping Lake, Huangshan Mountain, Jiaogang Lake, Tianzhu Mountain, Jiuhua Mountain and Huating Lake.

2. Add and adjust routes in this round of revision.

Add and adjust the route in this round of planning revisionArticle 112, total net increasemileage2322 kilometers;Among them, new56, with a net increase of 1,445 kilometers, 39 extensions, a net increase of 830 kilometers, and 17 local route adjustments, with a net increase of 47 kilometers. According to the route function, new and adjusted routes are divided into eight types:

——Accelerate regional integration development.Add and adjust routes19Article, including newArticle 11, such as Nanqiao–Pukou and Tiantangzhai-Luotian, Gaochun-Beaver Bridge, etc. extendfiveArticle, such as the holy spring.-Wangjiaba, etc. Local route adjustmentthreeArticles such as Hefei-Fuyang, etc.

-improve the level of inter-city connectivity.Add and adjust routes14 articles, including 8 new articles, such as Chulan-Lieshan and Zipeng.–South of the city, Daguan–Shuang Gang and others; extendsixStrip, such as the old bridge.-First class Lin.

-Deepen the coverage of economic nodes.Add and adjust routes19, including 15 new articles, such as Bai Liu.–Jinshe and Zhongguan-River map, Fuxing-Huikou, etc. Extend 4, such as Xuba.–Rivers, etc.

-strengthen the connectivity of transportation hubs.Add and adjust routes14 articles, including 6 new articles, such as double heap set.–Wugou and ancient city–Baogong, Huangshan West high-speed rail connection line, etc.; extend7, such as Dancheng-Xiyang, etc.; One local route adjustment, namely Maotan Factory-Sun.

-optimize the layout of the port-dredging highway.Add and adjust routes9 articles, including 5 new articles, such as osawa Township-Qi County, Gaohuang-Fenghuang, Shijian-Yanqiao, etc. Extend 4, such as Laozhou-Longtan.

-Promote cross-river (river) linkage development.Add and adjust routes7 articles, including 3 new articles, including new episodes.–Zaoxiang and Zhengyangguan–Saijian and Huayang–Incense corner; extend4, such as Huangwei-Zongpu.

-promote the deep integration of travel.Add and adjust routes7, including 4 new loop lines, including Jiaogang Lake, Tianzhu Mountain, Jiuhua Mountain and Huating Lake; Based on the planning and layout of scenic spots in southern Anhui and other regions, three scenic spots were added and adjusted, such as Taohuatan-du cun.

-Improve and optimize the road network layout.Add and adjust routes23 articles, including 3 new articles, including Zhuangli.–Shuoli and Leichi–Taici and Yansi–Xintan; extend7, such as Shiyang-ZhongYaoWait; Local route adjustmentArticle 13, such as Hanting-Wan ‘an, etc.

(3) Naming number

1. Numbering principle

(1) according to the order of radiation first, then vertical and horizontal lines, and then tie lines and loop lines;

(2) For the specific numbering rules, the national standard "Rules for Identification of Highway Routes and National Highway Numbers" (GB/T917 twenty17)；

(3) Contact lines numbered S4XX and S5XX, where S5XX is mainly the new route number for this round of revision;

(4) Loop, with independent field, numbered S6.XX。

2. Specific rules

(1) The number consists of 4 digits (S□□□), where "S" reflects the nature of the route as a provincial road; □□□□ is a number, reflecting the type and sequence of routes.

(2) □□□□: The first digit □ indicates the type, and the last two digits □□ indicate the order.

The beginning of "1" indicates the radiation from Hefei, and there are five in total (S101-S105).

The beginning of "2" indicates a vertical line, starting from the northern end of the route and ending at the southern end. They are arranged in the longitudinal direction of the route and numbered sequentially from east to west, totaling 55 (S201-S255).

The beginning of "3" indicates horizontal lines, starting from the eastern end of the route and ending at the western end. They are arranged horizontally and numbered sequentially from north to south, with a total of 48 lines (S301-S347、S34nine）。

"4" and "5" both indicate tie lines, and the starting point of the route is determined according to the direction (the north end of the north-south route is the starting point, and the east end of the east-west route is the starting point), and the starting points are numbered in sequence from north to south. If the starting points have the same latitude, they are numbered in sequence from east to west, totaling 131 (S401-S480, S501-S551).

The beginning of "6" indicates the loop line, and the newly added routes in this round are numbered from north to south, totaling 10 (S601-S610).

(D) the planning effect

1. Inter-provincial connectivity is closer.Plan to add provincial exits of ordinary provincial roads.one6, of which 8 are connected with the Yangtze River Delta and 8 are connected with the central region.eightA. The total number of provincial exports of ordinary countries and provinces isThe number of 137 has increased to 153, including 84 in the direction of the Yangtze River Delta (69 in Jiangsu and 15 in Zhejiang) and 68 in the direction of the central region (45 in Henan, 13 in Hubei and 10 in Jiangxi). The level of inter-provincial interconnection has been further improved, serving our province to link Shanghai, Jiangsu and Zhejiang and radiating the "two sectors" of the central and western regions, effectively strengthening the integration of the Yangtze River Delta,Development of the Yangtze River Economic Belt,midlandriseAnd other major strategic supporting roles have been significantly improved.

2. Important nodes cover a wider range.All towns and villages in the province,4A level and above scenic spots,Development zones and industrial parks above the provincial level are basically realized.onefiveGo to the ordinary national provincial highway within minutes to build"Three places and one district" and the construction of "seven strong provinces" provide strong support.

3. The layout across the river and Huaihe River is more perfect.The cross-river passage of ordinary national and provincial highways consists of8 to 10; The number of cross-Huai passages of provincial highways in ordinary countries has increased from 14 to 21, and the average spacing has changed from26Reduce kilometers to17 kilometers, the passage capacity has been significantly improved, which has promoted the comprehensive development of urban cross-river and cross-Huai integration.

fourIntegrated traffic connection is more efficient.All important transportation hubs in the province, such as important port areas, high-speed general interchange and high-speed railway station, have been realized.10Get on the provincial highway in minutes, noSignificantly improve the efficiency of connecting with the mode of transportation, and promote the development level of comprehensive transportation.effectivePromotion.

5. The function of highway dredging port is more perfect.This round of planning revision adds and adjusts ordinary provincial roads connecting important port areas.9, the total number of ordinary national and provincial roads connecting important port areas in the province.eightnineArticle, realize the province’s important port.100% coverageKey port areas along the Yangtze River, Huaihe River and Jianghuai Canal have been basically realized.Covered by two or more ordinary national highways, the port dredging capacity of highways has been further improved.

sixNetwork security and resilience have been significantly enhanced.Freeways and ordinary national and provincial highways are basically formed throughout the province.For the "one main and one standby" composite highway passage, the main skeleton of the comprehensive three-dimensional traffic network in the province basically realizes the road network layout form of "one main and multiple standby" and "double main and multiple standby", and the network reliability and facility safety are obviously improved.

Iv. implementation arrangements

arrive2025Accelerate the improvement of comprehensive transportation corridor in the Yangtze River Delta in,Strengthen interconnection with the central region,Advance firstprovinceInternational Unicom section construction; Accelerate the construction of the province-the first-class highway backbone network with three levels of connectivity between cities and counties will promote the upgrading and reconstruction of low-grade sections of ordinary provincial roads in key areas and the construction of sections to be connected. More than 2,000 kilometers of secondary and above ordinary provincial highways have been added, and the proportion of secondary and above highways is 60%.

2026-In 2035, we will continue to optimize the structure of ordinary provincial highways, continuously improve the level of inter-provincial and inter-city connectivity, and add secondary and above ordinary provincial highways.three600 kilometers, secondary and above roads account for 80%, of which secondary and above roads in southern Anhui and Dabie Mountains account for more than 70%, and other areas account for more than 85%.

arriveIn 2035, the total investment in the construction of ordinary provincial roads will be about2800100 million yuan, occupying about land.330,000 mu. Among them, 2025Years ago, the total investment in construction was about110 billion yuan, occupying about 130 thousand mu of land.

V. Environmental Impact and Countermeasures

(1) Environmental impact

Planning and implementation of ecological civilization construction requirements, attach importance to green development, planning and implementation need to occupy about330,000 mu of land consumes a certain amount of energy and produces carbon emissions; Some new lines have local spatial conflicts with environmentally sensitive targets such as nature reserves and drinking water sources and the red line of ecological protection, which have been avoided as much as possible in the planning and demonstration stage and will be further optimized in the implementation stage; Waste gas, sewage and noise generated during construction and operation may have certain impact on environmental quality. In the implementation stage, the environmental impact assessment system and the control requirements of "three lines and one order" (red line of ecological protection, bottom line of environmental quality, online utilization of resources, and access list of ecological environment) will be strictly implemented, and environmentally sensitive targets will be reasonably avoided and ecological environmental protection measures will be strengthened. The environmental impact generated by the planning is generally controllable.

(2) Countermeasures and measures

Strengthen ecological protection and restoration.Highway route selection avoids all kinds of environmentally sensitive targets to the maximum extent, and important sensitive areas that cannot be avoided need to cross (cross) from underground or air, and simultaneously carry out original vivid plant protection, wetland connection, wound ecological restoration and animal passage construction.

Strengthen the prevention and control of water environmental pollution.Try to avoid occupying the river and lake space, especially the drinking water source protection area. If it is occupied, it must be used."Closed" drainage and water treatment system, strengthen the sewage treatment during highway construction and operation, reuse the sewage as much as possible during construction, and conditionally incorporate the sewage into the urban sewage pipe network during operation.

Strengthen noise pollution prevention and control.Implement the requirements of noise protection distance in sensitive areas, set up sound barriers in key road sections that may cause noise pollution or take other effective measures to reduce noise.

Strengthen the prevention and control of environmental air pollution.The yard and unpaved pavement shall be watered frequently, and the location of lime-soil and asphalt mixing station and construction access road shall be selected reasonably to minimize the impact of the project on the air quality of nearby villages.

Strengthen the conservation and intensive use of resources.Make full use of traffic corridor resources, adopt advanced land-saving technologies and models, improve the comprehensive utilization rate of traffic infrastructure land, try not to occupy or occupy less cultivated land and basic farmland, promote the application of steel structure bridges, environmentally friendly and durable energy-saving materials, and promote the recycling of waste materials, facilities and equipment, water resources and the resource utilization of tunnel slag.

Strengthen environmental supervision and prevention.Strengthen environmental quality monitoring, ecological environmental protection and risk prevention. Timely discover major adverse environmental impacts and revise environmental protection measures; Establish and improve the ecological compensation mechanism and strengthen the protection and restoration of wild animals and plants; Strengthen the prevention of environmental risks such as vehicle oil spill and chemical leakage, and strengthen the construction of environmental risk emergency response capability.

VI. Safeguard measures

(1) Strengthen organizational leadership.Ordinary national provincial highwayimplement"Co-construction of provinces and cities and giving priority to cities"The people’s governments of cities and counties are responsible for the construction.Body. All localities should strengthen organizational leadership, establish and improve the mechanism of up-and-down linkage and departmental coordination, strengthen coordination and communication with neighboring provinces and cities, and jointly promote the simultaneous planning, construction and operation of inter-provincial and inter-city projects.

(2) Strengthen financial guarantee.We will continue to increase financial input at all levels, promote the improvement and implementation of a multi-channel fund-raising mechanism led by public financial input, and steadily improve the level of financial security. Make full use of the local government bond policy and increase the support of general bonds for ordinary provincial highway construction projects. Explore the joint development mode of common provincial highway construction and resources such as minerals, tourism and industry along the line, and introduce social capital to participate in the construction and operation. Actively strive for the support of financial institutions and constantly broaden financing channels.

(3) Do a good job in planning and implementation.Municipal and county people’s governments and relevant departments should incorporate the planning results into national economic and social development, land space and related special planning, in accordance with"Five-year plan-three-year rolling-annual plan" pushAdvance the mechanism, do a good job in major project construction,Track and master the progress of planned projects in time, strengthen dynamic evaluation,Pay close attention toStrengthen supervision over the implementation of new situations and problems arising in the implementation of the plan,Accelerate the implementation of the plan.

(4) Strengthen factor protection.Strengthen the coordination and overall planning with the land and space planning, and add new planning lines into the land and space basic information platforms at all levels as soon as possible and superimpose them on the land and space planning."One map" ensures the implementation of the project.Strictly implement the system of cultivated land protection and the system of economical and intensive land use, and improve the compound degree of traffic land and the utilization efficiency of land resources. Properly handle the relationship between ecological environmental protection and major infrastructure construction, give priority to avoiding environmentally sensitive areas, and adopt a harmless crossing method if it is really unavoidable. Increase support for land and forest use for transportation infrastructure construction, give priority to indicators, and ensure the demand for land and forest use for key projects.

On September 8th, at the national commendation meeting for fighting COVID-19 epidemic, General Secretary of the Supreme Leader delivered an important speech, which incisively summarized and profoundly explained the great anti-epidemic spirit of life first, national unity, risking one’s life and forgetting one’s death, respecting science and sharing common destiny.

In his nearly 10,000-word speech, General Secretary of the Supreme Leader mentioned "people" and "life" many times. He also explained the historical and cultural roots of the supremacy of life by using the old saying "love others and things is called benevolence", which fully demonstrated the profound heritage of Chinese civilization.

[Interpretation]

"Benevolence" is the ideological core of Confucianism, and Taoism also stresses "benevolence", which is where Confucianism and Taoism meet. However, the "benevolence" mentioned by Confucianism is mainly for people, and Zhuangzi’s "theory of uniformity of things" pushes "benevolence" to all things: "All things are universal, and heaven and earth are integrated." ("Zhuangzi Tianxia") advocates that "loving others and things is benevolence". To expand "benevolence" to a deeper level and a wider field, we should not only "love" but also "benefit". The so-called "benefiting things" means caring for all living and non-living substances in nature, which fully embodies the Taoist idea of harmony between man and nature and "harmony between man and nature".

[Interpretation]

"Love for others and things" is the traditional virtue of the Chinese nation and the spiritual bond on which the Chinese nation depends for its survival and development, which has been fully demonstrated in the process of fighting the epidemic.

The COVID-19 epidemic is a major public health emergency with the fastest spread, the widest infection range and the most difficult prevention and control in China since the founding of New China. It is also a crisis and a big test for China. In the face of the sudden severe epidemic, General Secretary of the Supreme Leader personally commanded and deployed, taking overall situation into consideration and making decisive decisions, which strengthened confidence, consolidated strength and pointed out the direction for the people of China to fight the epidemic. With the mission of being highly responsible to the people, the CPC Central Committee has always put the people’s life safety and physical health first, earnestly adhered to the people-centered development idea, and spared no expense in the short-term "shutdown" of the economy and the enormous financial pressure, but also concentrated all resources and tried every means to fight the epidemic. Mobilize the best doctors, the most advanced equipment and the most urgently needed resources throughout the country, and go all out to invest in disease treatment; In the process of treatment, no infected person is left out, and every patient is not abandoned, so as to realize "all due, all cured, all checked and all separated". From the baby born just over 30 hours to the elderly over 100 years old, all the treatment expenses are borne by the state … … Looking back on the course of anti-epidemic, people first and life first are the distinctive background of China’s anti-epidemic, and it is the general consensus of China society to try our best to save lives.

Under the guidance of the Supreme Leader General Secretary, China has created countless life miracles and achieved great strategic achievements in the fight against epidemic diseases. The 1.4 billion people of China have helped each other in the same boat, fought side by side, overcome difficulties together, and written a great chapter in the struggle against major infectious diseases with practical actions. As General Secretary of the Supreme Leader said: "It is the people of Chinese who have given us strength and confidence to overcome this epidemic." "The people are the real heroes. As long as we rely closely on the people, we will be able to overcome all difficulties and obstacles and realize the great rejuvenation of the Chinese nation. "　

The people are only the country, and the country is better. A country that cherishes the people will prosper, and a political party that seeks happiness for the people will have a lasting foundation.(Author Yang Lixin)

(Central Radio and Television General Station CCTV Network)

Cctv newsAccording to the website of the Ministry of Science and Technology, the Detailed Rules for the Implementation of the Regulations on the Management of Human Genetic Resources was deliberated and adopted at the 3rd ministerial meeting of the Ministry of Science and Technology on May 11, 2023, and is hereby promulgated and shall come into force as of July 1, 2023.

Detailed rules for the implementation of the regulations on the management of human genetic resources

Chapter I General Principles

　　the first 　In order to effectively protect and rationally utilize China’s human genetic resources, and safeguard public health, national security and social public interests, these Detailed Rules are formulated in accordance with the Biosafety Law of People’s Republic of China (PRC), Regulations of People’s Republic of China (PRC) on the Management of Human Genetic Resources (hereinafter referred to as the Regulations) and other relevant laws and administrative regulations.

　　the second 　The collection, preservation, utilization and provision of China’s human genetic resources shall abide by these detailed rules.

　　The information of human genetic resources mentioned in Article 2 of the Regulations includes information materials such as human genes and genome data generated by using human genetic resources.

　　The information of human genetic resources mentioned in the preceding paragraph does not include clinical data, imaging data, protein data and metabolic data.

　　Article 　The Ministry of Science and Technology (hereinafter referred to as the Ministry of Science and Technology) is responsible for the management of national human genetic resources investigation, administrative licensing, supervision and inspection, and administrative punishment.

　　The Ministry of Science and Technology entrusts relevant organizations according to law to carry out formal examination and technical review of the application materials for administrative license of human genetic resources, as well as filing, prior reporting, supervision and inspection and administrative punishment of human genetic resources.

　　Article 4 　The Science and Technology Departments (commissions and bureaus) of provinces, autonomous regions and municipalities directly under the Central Government and the Science and Technology Bureau of Xinjiang Production and Construction Corps (hereinafter referred to as the provincial administrative department of science and technology) are responsible for the management of the following human genetic resources in this region:

　　(1) Supervision, inspection and daily management of human genetic resources;

　　(two) investigation and handling of illegal cases of human genetic resources within the scope of their functions and powers;

　　(three) according to the Ministry of science and technology, to carry out the investigation of human genetic resources in this region, the administrative licensing of human genetic resources, and the investigation and handling of illegal cases of human genetic resources.

　　Article 5 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall strengthen the supervision of human genetic resources, equip administrative law enforcement personnel, carry out supervision and inspection of human genetic resources activities according to their functions and powers, and perform their duties of supervision and management of human genetic resources according to law.

　　Article 6 　The Ministry of Science and Technology employs experts in life science and technology, medicine, health, ethics, law and information security to form an expert advisory committee on human genetic resources management to provide decision-making consultation and technical support for the management of human genetic resources throughout the country.

　　Article 7 　The Ministry of Science and Technology supports the rational use of human genetic resources to carry out scientific research, develop biomedical industry, improve diagnosis and treatment technology, strengthen management and supervision of human genetic resources, optimize examination and approval services, improve examination and approval efficiency, promote standardization of examination and approval and information disclosure, and improve management and service levels.

Chapter II General Requirements

　　Article 8 　The collection, preservation, utilization and external provision of China’s human genetic resources shall conform to ethical principles and pass the ethical review of the ethics (review) Committee that has been filed with the relevant administrative departments. Ethical review shall comply with laws, administrative regulations and relevant provisions of the state.

　　Article 9 　The collection, preservation, utilization and external provision of human genetic resources in China shall respect and protect the rights and interests of providers of human genetic resources, such as privacy and personal information, and obtain written informed consent according to regulations to ensure that the legitimate rights and interests of providers of human genetic resources are not infringed.

　　Article 10 　The collection, preservation, utilization and external provision of China’s human genetic resources shall comply with the relevant requirements and technical specifications of scientific and technological activities, including but not limited to standards, norms and procedures.

　　Article 11 　The collection and preservation of China’s human genetic resources in China or the provision of China’s human genetic resources abroad must be carried out by China’s scientific research institutions, universities, medical institutions or enterprises (hereinafter referred to as Chinese units). Domestic-funded real control institutions located in Hong Kong and Macao are regarded as Chinese units.

　　Overseas organizations, institutions established or actually controlled by overseas organizations and individuals (hereinafter referred to as foreign units) and overseas individuals shall not collect and preserve China’s human genetic resources within China, and shall not provide China’s human genetic resources to overseas.

　　Article 12 　The institutions established or actually controlled by overseas organizations and individuals mentioned in Article 11 of these Rules include the following situations:

　　(a) overseas organizations and individuals hold or indirectly hold more than 50% of the shares, equity, voting rights, property shares or other similar rights and interests of the institution;

　　(2) Overseas organizations and individuals hold or indirectly hold less than 50% of the shares, equity, voting rights, property shares or other similar rights and interests of the institution, but their voting rights or other rights and interests are sufficient to dominate or exert significant influence on the decision-making and management of the institution;

　　(three) overseas organizations and individuals through investment relations, agreements or other arrangements, enough to dominate or exert significant influence on the decision-making and management of institutions;

　　(4) Other circumstances stipulated by laws, administrative regulations and rules.

　　Article 13 　Units that collect, preserve, utilize and provide China’s human genetic resources to the outside world shall strengthen the construction of management systems, review the purposes and research plans of scientific research involving human genetic resources, and ensure the legitimate use of human genetic resources.

　　Article 14 　To use China’s human genetic resources to carry out international scientific research cooperation, we should ensure that Chinese units and their researchers participate in the whole process and substantially, and share relevant rights and interests according to law. In the process of international scientific research cooperation, all records, data and information generated by using China’s human genetic resources should be completely open to Chinese units, and backup should be provided to Chinese units.

　　Article 15 　The Ministry of Science and Technology has strengthened the informatization construction of human genetic resources management, established an open and unified information system platform for administrative licensing, filing and safety review of human genetic resources, provided convenience for applicants to handle administrative licensing, filing and other matters through the Internet, promoted real-time dynamic management, and realized traceability and inquiry of human genetic resources management information.

　　Article 16 　The Ministry of Science and Technology, together with relevant departments of the State Council and provincial administrative departments of science and technology, will promote the preservation of human genetic resources by scientific research institutions, institutions of higher learning, medical institutions and enterprises in China according to laws and regulations, and promote the construction of standardized and standardized basic platforms and big data for the preservation of human genetic resources, and open them to relevant scientific research institutions, institutions of higher learning, medical institutions and enterprises in accordance with relevant state regulations.

　　Article 17 　In response to public health emergencies and other emergencies, the Ministry of Science and Technology has established a rapid examination and approval mechanism, and the application for administrative license of human genetic resources involved in emergency response should be expedited.

　　The Ministry of Science and Technology shall, in accordance with the principle of unified command, high efficiency and scientific examination and approval, speed up the organization of the acceptance, evaluation and examination of the application for administrative license. The circumstances, procedures, time limits and requirements of quick approval shall be stipulated separately by the Ministry of Science and Technology.

　　Article 18 　The Ministry of Science and Technology has formulated and timely released service guides and demonstration texts for the collection, preservation, utilization and external provision of human genetic resources in China, providing convenient and professional guidance and services for applicants to handle administrative licensing and filing of human genetic resources.

　　Article 19 　The Ministry of Science and Technology regularly trains scientific researchers and managers of relevant departments engaged in the collection, preservation, utilization and external provision of human genetic resources, so as to enhance their legal awareness and sense of responsibility and enhance their management and service capabilities.

　　Article 20 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall establish and constantly improve the measures to prevent and control the risks of clean government, improve the supervision and restriction mechanism, and strengthen the supervision of the important links and key positions in the management of human genetic resources in their own organs.

Chapter III Investigation and Registration

　　Article 21 　The Ministry of Science and Technology is responsible for organizing the national survey of human genetic resources. Entrusted by the Ministry of Science and Technology, the provincial administrative department of science and technology is responsible for the investigation of human genetic resources in this region.

　　Article 22 　The national survey of human genetic resources is carried out every five years, and can be carried out according to actual needs when necessary.

　　Article 23 　The Ministry of Science and Technology organizes experts in related fields to formulate a national work plan for the investigation of human genetic resources. The provincial administrative department of science and technology shall, after completing the investigation of human genetic resources in this region, timely summarize the survey data and information obtained and submit them to the Ministry of Science and Technology.

　　Article 24 　On the basis of the national survey of human genetic resources, the Ministry of Science and Technology organized research on important genetic families and human genetic resources in specific areas, gradually established an inventory of important genetic families and human genetic resources in specific areas in China, and revised and improved it in a timely manner.

　　Article 25 　The Ministry of Science and Technology is responsible for the registration of important genetic families and human genetic resources in specific areas, formulating management measures for declaration and registration, and establishing an information service platform for declaration and registration management.

　　Article 26 　Scientific research institutions, institutions of higher learning, medical institutions and enterprises in China shall timely declare important genetic families and human genetic resources in specific areas through the registration management information service platform.

Chapter IV Administrative Licensing and Filing

Section 1 Administrative License for Collection and Preservation

　　Article 27 　The administrative license for the collection of human genetic resources is applicable to the following activities to be carried out in China:

　　(1) Collection activities of human genetic resources of important genetic families. An important genetic family refers to a blood-related group with hereditary diseases, hereditary special physique or physiological characteristics, and the members of this group with hereditary diseases and hereditary special physique or physiological characteristics involve three or more generations, excluding common diseases such as hypertension, diabetes, red-green color blindness and hemophilia. Important genetic families discovered for the first time shall be declared in a timely manner in accordance with the provisions of Article 26 of these Rules.

　　(2) Collection activities of human genetic resources in specific areas. Human genetic resources in a specific area refer to those that have lived in isolation or special environment for a long time and have special physical characteristics or adaptive traits in physiological characteristics. Specific areas are not divided according to whether they are inhabited by ethnic minorities.

　　(three) for large-scale population research and the number of people more than 3000 cases of human genetic resources collection activities. Large-scale population studies include but are not limited to cohort studies, cross-sectional studies, clinical studies, and physical studies. The collection of human genetic resources involved in clinical trials to obtain the marketing license of related drugs and medical devices in China is not included, and there is no need to apply for an administrative license for the collection of human genetic resources.

　　Article 28 　The administrative license for the preservation of human genetic resources is applicable to the activities of preserving human genetic resources in China and providing a basic platform for scientific research.

　　The preservation of human genetic resources refers to the act of preserving human genetic resources with legal sources in suitable environmental conditions to ensure their quality and safety for future scientific research, excluding the temporary storage for teaching purposes after laboratory testing in accordance with the requirements of laws and regulations or clinical research programs.

　　Article 29 　Where the activities for the preservation of human genetic resources that should be applied for administrative license involve the collection of human genetic resources at the same time, the applicant only needs to apply for the administrative license for the preservation of human genetic resources, and does not need to apply for the administrative license for the collection of human genetic resources separately.

　　Article 30 　The entity preserving human genetic resources shall, in accordance with the provisions of Article 15 of the Regulations, submit an annual report on its preservation of human genetic resources in the previous year to the Ministry of Science and Technology before January 31 of each year. The annual report shall contain the following contents:

　　(1) The preserved human genetic resources;

　　(2) Information on the source and use of human genetic resources;

　　(three) the implementation of the management system related to the preservation of human genetic resources;

　　(4) Maintenance and changes of the sites, facilities and equipment used by the entity to preserve human genetic resources;

　　(five) the change of the main management personnel responsible for the preservation work of this unit.

　　Units that preserve human genetic resources shall strengthen management to ensure that the preserved human genetic resources come from legal sources. The Ministry of Science and Technology organizes provincial administrative departments of science and technology to conduct spot checks on the preservation activities of human genetic resources preservation units in this region every year.

Section 2 Administrative Licensing and Filing of International Cooperation

　　Article 31 　The application for the administrative license of international scientific research cooperation on human genetic resources shall pass the ethical examination of the countries (regions) where the two parties are located. If the foreign unit is really unable to provide the certification materials for the ethical review of the host country (region), it may submit the certification materials that the foreign unit approves the ethical review opinions of the Chinese unit.

　　Article 32 　In order to obtain the marketing license of related drugs and medical devices in China, if the clinical medical and health institutions use China’s human genetic resources to carry out international cooperative clinical trials, which do not involve the exit of human genetic resources materials, approval is not required, but it shall meet one of the following circumstances, and the types, quantities and uses of human genetic resources to be used shall be filed with the Ministry of Science and Technology before the clinical trials are carried out:

　　(1) The collection, detection and analysis of human genetic resources and the disposal of the remaining human genetic resources are carried out in clinical medical and health institutions;

　　(2) The human genetic resources involved are collected in clinical medical and health institutions, and the domestic units designated by the clinical trial scheme for marketing licenses of related drugs and medical devices are tested, analyzed and the remaining samples are processed.

　　The clinical medical and health institutions mentioned in the preceding paragraph refer to medical institutions and disease prevention and control institutions that have filed with relevant departments in China and conducted clinical trials according to law.

　　In order to obtain the exploratory research part involved in the clinical trial of relevant drugs and medical devices listed in China, an administrative license for international scientific research cooperation of human genetic resources should be applied.

　　Article 33 　The administrative license for international scientific research cooperation and the filing of international cooperative clinical trials shall be jointly applied by Chinese units and foreign units. All parties to the cooperation shall make a commitment to the authenticity, accuracy and completeness of the application materials and information.

　　If the international scientific research cooperation and international cooperative clinical trial of human genetic resources to be carried out involve multi-center clinical research, it shall not apply for administrative license or filing after splitting.

　　Article 34 　To carry out multi-center clinical research, the leader unit can apply for administrative license or filing by the applicant or leader unit after passing the ethical review.

　　After the applicant or the leader unit has obtained the administrative license or completed the filing, the medical and health institutions participating in the clinical research will submit the certification materials of the ethical review documents of the unit or the approval documents provided by the leader unit and the commitment letter issued by the unit to the Ministry of Science and Technology, and then the international cooperative clinical research can be carried out.

　　Article 35 　Both parties who have obtained the administrative license for international scientific research cooperation or completed the filing of international cooperative clinical trials shall jointly submit a report on cooperative research to the Ministry of Science and Technology within six months after the expiration of the effective period of the administrative license or filing. The report on cooperative research shall contain the following contents:

　　(a) changes in the purpose and content of the study;

　　(two) the implementation of the research program;

　　(three) the completion of the research content;

　　(four) the use and disposal of human genetic resources in China;

　　(five) all records in the research process and the recording, storage and use of data and information;

　　(six) the whole process and substantial participation of Chinese units and their researchers in the research and the participation of foreign units in the research;

　　(seven) the output, ownership and distribution of rights and interests of research results;

　　(eight) the ethical review involved in the study.

Section 3 Prior Report on External Provision and Open Use

　　Article 36 　If the information of human genetic resources is provided or made available to overseas organizations, individuals and institutions established or actually controlled by them, the Chinese information owner shall report to the Ministry of Science and Technology in advance and submit information backup. To report to the Ministry of Science and Technology in advance, the following information shall be submitted:

　　(a) the purpose and purpose of providing or opening up the use of information on human genetic resources in China to overseas organizations and individuals and institutions established or actually controlled by them;

　　(2) Providing or opening up the use of China’s human genetic resources information and information backup to overseas organizations and individuals and institutions established or actually controlled by them;

　　(3) Basic information about overseas organizations and individuals receiving information on human genetic resources and the institutions established or actually controlled by them;

　　(4) Providing or opening up the potential risk assessment of the protection of human genetic resources in China to overseas organizations and individuals and their established or actually controlled institutions.

　　During the implementation of international scientific research cooperation that has obtained administrative license or international cooperative clinical trials that have been filed, if the Chinese unit provides the information of human genetic resources produced by the cooperation to the foreign unit, if it has been agreed in the international cooperation agreement that it will be used by both parties, it is not necessary to report in advance and submit information backup separately.

　　Article 37 　The provision or open use of human genetic resources information to overseas organizations, individuals and institutions established or actually controlled by them may affect China’s public health, national security and social public interests, and shall pass the safety review organized by the Ministry of Science and Technology.

　　The situations that should be reviewed for safety include:

　　(1) Information on human genetic resources of important genetic families;

　　(2) Information on human genetic resources in specific areas;

　　(3) Exon sequencing and genome sequencing information resources with more than 500 cases;

　　(four) other circumstances that may affect China’s public health, national security and social public interests.

　　Article 38 　The Ministry of Science and Technology shall, jointly with relevant departments, formulate safety review rules, organize experts in relevant fields to conduct safety assessment, and make a review decision according to the safety assessment opinions.

　　In the process of exporting human genetic resources, if the related items involve the scope of export control, they must abide by the national export control laws and regulations.

The fourth section administrative licensing, filing and prior reporting process

　　Article 39 　If the applicant’s application materials are complete and the form meets the requirements, the Ministry of Science and Technology shall accept and issue a paper or electronic certificate stamped with a special seal and dated.

　　If the application materials are incomplete or inconsistent with the statutory form, the Ministry of Science and Technology shall inform the applicant of all the contents that need to be supplemented at one time within five working days from the date of receiving the formal application materials.

　　Article 40 　The Ministry of Science and Technology shall set up an expert database and establish an expert management system according to the needs of technical review and safety review.

　　The Ministry of Science and Technology selects evaluation experts from the expert database in a random way, conducts technical evaluation on the application for administrative license of human genetic resources, and conducts safety assessment on the external provision or open use of human genetic resources information that should be subject to safety review. Technical review opinions and safety assessment opinions are used as reference for making administrative licensing decisions or safety review decisions.

　　Experts generally participate in technical review and safety review by network, and when necessary, they can use meetings, on-site surveys and other means.

　　Article 41 　The Ministry of Science and Technology shall, within 20 working days from the date of acceptance, make an administrative licensing decision on the application for administrative licensing of human genetic resources. If an administrative licensing decision cannot be made within twenty working days, it may be extended for ten working days with the approval of the person in charge of the Ministry of Science and Technology, and the reasons for the extension shall be informed to the applicant.

　　Article 42 　When the Ministry of Science and Technology makes a decision on administrative licensing, which requires hearing, inspection, inspection, quarantine, appraisal and technical review according to law, the time required shall not be counted within the time limit specified in Article 41 of these Detailed Rules, but the applicant shall be informed in writing of the time required.

　　Article 43 　After the Ministry of Science and Technology makes a decision on administrative license, it shall inform the applicant in writing of the decision on administrative license and send a copy to the provincial administrative department of science and technology where the applicant is located.

　　A decision to grant an administrative license according to law shall be made public on the website of the Ministry of Science and Technology. If a decision is made not to grant an administrative license according to law, the reasons shall be explained, and the applicant shall be informed of the right to apply for administrative reconsideration or bring an administrative lawsuit according to law.

　　Article 44 　After obtaining the administrative license for the collection of human genetic resources, the licensee shall apply to the Ministry of Science and Technology for changes in major matters such as the participating units, collection purposes, collection plans or collection contents.

　　Article 45 　After obtaining the administrative license for the preservation of human genetic resources, the licensee shall apply to the Ministry of Science and Technology for changes in the purpose, scheme or content of preservation.

　　Article 46 　After obtaining the administrative license for international scientific research cooperation on human genetic resources, in the process of international scientific research cooperation, the purpose and content of the research change, the type, quantity and use of human genetic resources involved in the research plan change, or other important matters such as the sponsor, the leader unit, the contract research organization and the third-party laboratory change, the licensee shall apply to the Ministry of Science and Technology for change.

　　Article 47 　After obtaining the administrative license for international scientific research cooperation on human genetic resources, the licensee does not need to apply for change in any of the following circumstances, but shall submit a written explanation of the change and corresponding materials to the Ministry of Science and Technology:

　　The research content or research plan remains unchanged, and only involves the change that the total amount does not exceed 10% of the approved amount;

　　The participating units other than the cooperative units listed in Article 46 of these Rules are changed;

　　The name of the partner unit is changed;

　　The research content or research plan is changed, but it does not involve the change of the type, quantity and use of human genetic resources, or the content after the change is not beyond the approved scope.

　　Article 48 　If the licensee applies for changes to the matters listed in Articles 44 to 46 of these Rules, the Ministry of Science and Technology shall review and make a decision on whether to approve the changes. Meet the statutory conditions and standards, the Ministry of science and technology should be changed.

　　Procedures such as acceptance, examination, processing time limit, decision and notification of the application for change shall be implemented with reference to the provisions of Articles 39 to 43 of these Detailed Rules on the application for administrative license.

　　Article 49 　Before the decision on administrative license is made, if the applicant withdraws his application in writing, the Ministry of Science and Technology will terminate the examination of the application for administrative license.

　　Article 50 　Under any of the following circumstances, the Ministry of Science and Technology may revoke the administrative license of human genetic resources at the request of interested parties or according to its functions and powers:

　　(a) breach of privilege, dereliction of duty to make a decision to approve the administrative license;

　　(two) beyond the statutory authority to make a decision to approve the administrative license;

　　(3) Making a decision to grant an administrative license in violation of legal procedures;

　　(4) granting an administrative license to an applicant who is not qualified to apply or does not meet the statutory requirements;

　　(five) other circumstances in which the administrative license can be revoked according to law.

　　If the licensee obtains the administrative license by cheating, bribery or other improper means, the Ministry of Science and Technology shall revoke it.

　　If the administrative license is revoked in accordance with the provisions of the preceding two paragraphs, which may cause great harm to the public interest, it shall not be revoked.

　　Article 51 　To apply for the filing of international cooperative clinical trials, the approval documents, notices or filing and registration materials of clinical trials of the drug supervision and administration department shall be obtained in advance.

　　Article 52 　To apply for the filing of international cooperative clinical trials, the following materials shall be submitted:

　　(a) the basic situation of the parties to the cooperation;

　　(2) The types, quantities and uses of human genetic resources involved in the study;

　　(3) Research plan;

　　(four) the approval of the ethical review of the leader unit;

　　(5) Other supporting materials.

　　Article 53 　After the international cooperative clinical trial is put on record, if the types, quantities and uses of human genetic resources involved change, or if the partners, research schemes, research contents and research purposes change, the filer shall timely handle the filing changes.

　　If the change of research plan or research content does not involve the change of the type, quantity and use of human genetic resources, it is not necessary to go through the filing change, but a written explanation of the change and corresponding materials shall be submitted to the Ministry of Science and Technology before the change activity begins.

　　Article 54 　After providing or opening the use of human genetic resources information to overseas organizations, individuals and institutions established or actually controlled by them, and reporting to the Ministry of Science and Technology in advance, if the purpose and recipient of the information change, it shall submit a change report to the Ministry of Science and Technology before the implementation of the change.

　　Article 55 　If the licensee needs to extend the validity of the administrative license, it shall apply to the Ministry of Science and Technology 30 working days before the expiration of the validity of the administrative license. The Ministry of Science and Technology shall, according to the application of the licensee, make a decision on whether to approve the extension before the expiration of the validity period of the administrative license; If no decision is made within the time limit, it shall be deemed that the extension is granted.

　　If the filer needs to extend the validity period of filing, he shall apply to the Ministry of Science and Technology 30 working days before the expiration of the validity period of filing. The Ministry of science and technology shall complete the continuation of the record before the expiration of the validity period of the record; If it is not completed within the time limit, it shall be deemed as having completed the continuation of filing.

Chapter V Supervision and Inspection

　　Article 56 　The Ministry of Science and Technology is responsible for the national supervision and inspection of human genetic resources, and the provincial administrative departments of science and technology are responsible for the supervision and inspection of human genetic resources in this region. The supervision and inspection items mainly include:

　　(a) the collection, preservation, utilization and external supply of human genetic resources, the implementation of the main responsibility of the relevant units, the establishment, improvement and implementation of relevant rules and regulations;

　　(2) Information on the collection, preservation and utilization of human genetic resources by the relevant units that have been approved for the human genetic resources project, and information on the exit, external provision, open use and use after leaving the country;

　　(three) the disposal of surplus materials, intellectual property rights and benefit sharing of human genetic resources;

　　(four) the authenticity of the record items of human genetic resources;

　　(five) other matters that the Ministry of Science and Technology or the provincial administrative department of science and technology think need supervision and inspection.

　　Article 57 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall prepare the annual supervision and inspection plan and implement the risk management of human genetic resources.

　　The annual supervision and inspection plan shall include inspection items, inspection methods, inspection frequency, sampling items and sampling proportion.

　　Article 58 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall increase the frequency of supervision and inspection of units that have been subjected to administrative punishment for illegal acts of human genetic resources in the past three years, that have not been corrected in time because of the management risks of human genetic resources, and that have been recorded in the relevant disciplinary list of dishonesty, and incorporate them into the annual daily supervision and inspection plan and carry out supervision and inspection. Units that have significantly improved their management system and management norms and have not committed illegal acts again may reduce the frequency of supervision and inspection in a timely manner.

　　Article 59 　For other units other than those specified in Article 58 of these Detailed Rules, the Ministry of Science and Technology and the provincial administrative department of science and technology can randomly determine the supervision and inspection items within the scope of human genetic resources activities of the unit, and randomly select supervision and inspection personnel to carry out supervision and inspection.

　　Article 60 　In case of serious illegal acts or temporary and unexpected tasks, as well as problems found through complaints, transfer, data monitoring, etc., the Ministry of Science and Technology and the provincial administrative department of science and technology can deploy and carry out special supervision and inspection.

　　Article 61 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall timely record and summarize the daily supervision and inspection information of human genetic resources activities, and improve the daily supervision and inspection measures.

　　Article 62 　When it is found that the subject of supervision and inspection may have the risk of violating the relevant provisions of the Regulations, the Ministry of Science and Technology or the provincial administrative department of science and technology may conduct administrative interviews with its legal representative and principal responsible person.

　　Article 63 　If it is found that the object under supervision and inspection may violate the provisions of the Regulations, the Ministry of Science and Technology or the provincial administrative department of science and technology shall investigate and take the following measures when necessary:

　　(1) Taking measures such as recording, copying, photographing and video recording according to law;

　　(two) to take administrative compulsory measures such as sealing up and detaining according to law;

　　(3) Conducting inspection, inspection, quarantine or appraisal of related articles according to law.

　　Article 64 　The Ministry of Science and Technology or the provincial administrative department of science and technology shall implement administrative compulsory measures in accordance with the procedures stipulated in the Administrative Compulsory Law of the People’s Republic of China.

　　Article 65 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall adopt or terminate administrative compulsory measures with the approval of the person in charge of this organ.

　　Where compulsory measures of seizure or detention are implemented according to law, a decision and list of seizure or detention shall be made and delivered to the parties on the spot. In case of emergency, failure to seal up or detain in time may affect the investigation of the case, or there are hidden dangers that may lead to the damage and loss of human genetic resources, you can seal up or detain in advance, and fill in a decision on sealing up or detaining within 24 hours and serve it on the parties concerned.

Chapter VI Administrative Punishment

　　Article 66 　The Ministry of Science and Technology and the provincial administrative department of science and technology shall standardize the exercise of administrative penalty discretion of human genetic resources, comprehensively consider the facts, nature, circumstances and degree of social harm of illegal acts, reasonably determine the types and extent of administrative penalties within the scope stipulated in the Regulations, ensure that the penalty is equivalent, and prevent the abnormal light and heavy.

　　The discretion standard of administrative punishment for human genetic resources shall be separately formulated by the Ministry of Science and Technology and announced to the public.

　　Article 67 　Before making a decision on administrative punishment, the Ministry of Science and Technology and the provincial administrative department of science and technology shall inform the parties in writing of the contents, facts, reasons and basis of the proposed administrative punishment, and inform them that they have the right to make statements and defend themselves according to law. If the administrative penalty to be imposed falls within the scope of hearing, the party concerned shall also be informed of the right to request a hearing.

　　If a party exercises a statement, defend oneself or requests a hearing, it shall submit it in writing within five working days from the date of service of the notification. If it fails to do so within the time limit, it shall be deemed as giving up the above rights.

　　The Ministry of Science and Technology and the provincial administrative department of science and technology shall not give heavier punishment for the statements, defenses or hearings of the parties.

　　Article 68 　The Ministry of Science and Technology or the provincial administrative department of science and technology intends to make the following administrative punishment decision, and if the party requests a hearing, it shall organize a hearing:

　　(1) Imposing a fine of more than 1 million yuan on a legal person or other organization or a fine of more than 100,000 yuan on a citizen;

　　(2) Confiscating the illegal income of legal persons and other organizations of more than 3 million yuan or confiscating the illegal income of citizens of more than 300,000 yuan;

　　(3) It is forbidden to engage in the activities of collecting, preserving, utilizing and providing human genetic resources in China for more than one year;

　　(4) Failing to accept the application for administrative license of human genetic resources for more than two years;

　　(5) Revoking the administrative license of human genetic resources that has been obtained;

　　(6) Other circumstances in which a hearing shall be organized as stipulated by laws and administrative regulations.

　　Article 69 　Before the Ministry of Science and Technology or the provincial administrative department of science and technology makes a decision on administrative punishment of human genetic resources, the case handling institution of this department shall send the proposed administrative punishment decision and case materials to the working institution responsible for legal review of this department for legal review. No decision shall be made without legal examination or examination.

　　If the administrative penalty decision to be made only involves a warning, there is no need for legal review.

　　Article 70 　After the decision on administrative punishment is made, the Ministry of Science and Technology or the provincial administrative department of science and technology shall, within seven working days, serve the decision on administrative punishment on the parties concerned or other legal recipients in accordance with relevant laws and regulations.

　　Article 71 　The decision on administrative punishment shall be made within 90 days from the date of filing the case. If the case is complicated and the decision on administrative punishment cannot be made within 90 days, it may be extended for 90 days with the approval of the person in charge of this organ. If the case is particularly complicated and the decision on administrative punishment cannot be made after the extension, the person in charge of this organ shall decide whether to continue the extension through collective discussion. Where an extension is decided, a reasonable extension period shall be determined at the same time, but the longest extension period shall not exceed 60 days.

　　In the process of handling a case, the time of hearing, announcement, inspection, inspection, quarantine, appraisal, audit and suspension shall not be included in the time limit for handling a case referred to in the first paragraph of this article.

　　Article 72 　The illegal gains stipulated in Articles 36, 39, 41, 42 and 43 of the Regulations shall be calculated by deducting appropriate reasonable expenses from all the income obtained from the implementation of illegal acts; If it is difficult to calculate, the value of human genetic resources involved in the illegal act or the amount of funds invested for human genetic resources shall be regarded as illegal income.

　　Article 73 　In the supervision and inspection of human genetic resources or the investigation and handling of illegal cases, it is found that the relevant citizens, legal persons or other organizations do not have the storage conditions for human genetic resources, and the Ministry of Science and Technology or the provincial administrative department of science and technology shall organize the transfer of their stored human genetic resources to a unit with storage conditions for temporary storage.

　　Article 74 　The provincial administrative department of science and technology shall, within fifteen working days from the date of making the decision on administrative punishment, submit a copy of the case handling and the decision on administrative punishment to the Ministry of Science and Technology.

　　Article 75 　The Ministry of Science and Technology has the right to supervise the administrative punishment of human genetic resources implemented by the provincial administrative department of science and technology, and order the relevant illegal or improper acts to make corrections according to law.

Chapter VII Supplementary Provisions

　　Article 76 　The provisions concerning the time limit in these Detailed Rules are marked as working days, excluding legal holidays; If it is not indicated as a working day, it is a natural day.

　　Article 77 　The "above" and "not exceeding" mentioned in these Detailed Rules all include this number, while "greater than" and "insufficient" do not include this number.

　　Article 78 　These Rules shall come into force as of July 1, 2023.

　　Attention, Hebei people!

　　It is estimated that tomorrow night to the 9th.

　　Our province will experience another precipitation process.

　　There are showers or thunderstorms in the province.

　　There is moderate to heavy rain in some areas.

　　There is a local rainstorm.

　　↓↓↓

　　Tomorrow night to the 9th.

　　Hebei welcomes rain again

　　Today and tomorrow, most areas in Hebei are mainly sunny, and thunderstorms are just embellishments; It is expected that from tomorrow night to the 9th, our province will experience another precipitation process, with showers or thunderstorms in the whole province, moderate to heavy rain in some areas, local heavy rain and strong convective weather.

　　Please continue to pay attention to the latest forecast and early warning information and strengthen prevention.

　　Specific forecast

　　Hebei Meteorological Observatory issued the weather forecast at 11: 00 on September 6, 2023:

　　From this afternoon to the night, the whole province is sunny and cloudy.

　　Tomorrow during the day, the northwest of Zhangjiakou will turn cloudy with scattered showers or thunderstorms, and other areas will turn sunny to cloudy. There are 5 to 6 southwest winds and 7 to 8 gusts in Bashang area.

　　From tomorrow night to the 8th, there will be cloudy showers or thunderstorms in the areas north of Baoding and Langfang, including moderate to heavy rain in Zhangjiakou and northern Chengde, and heavy rain in some places. The precipitation is accompanied by strong convective weather such as short-term heavy precipitation and short-term strong wind, and other areas are cloudy.

　　From the night of the 8th to the 9th, there were showers or thunderstorms in most parts of the province, with moderate to heavy rain in the central and southern areas and heavy rain in the local area. The precipitation was accompanied by strong convective weather such as short-term heavy precipitation and short-term strong wind.

　　Next three days

　　The heat sensation is obvious during the daytime.

　　Today, during the daytime, most areas of our province will be shrouded in heat. It is estimated that the highest temperature in the province will be 30 C and above, and the highest temperatures in Chengde, Langfang and Hengshui will be around 34 C.

　　The temperature of tomorrow and the day after tomorrow is basically the same pattern, so we should pay attention to heatstroke prevention at noon.

　　(Langfang temperature trend source Central Meteorological Observatory)

　　However, after all, it is going to be the Millennium season soon. The heat is only temporary, and the coolness is the correct way to open this season. It is expected that the temperature will drop on the 9th. Take Baoding as an example, the highest temperature will be around 32℃ from the 6th to the 8th, and it will plummet to 25℃ on the 9th.

　　Cold air will bring rain while cooling down. At the turn of summer and autumn, there will be a rain and a cold. Please pay attention to the weather and temperature changes at any time.

　　(Baoding temperature trend source Central Meteorological Observatory)

　　Forecast of major cities in Hebei

　　Great Wall Network synthesizes the weather in Hebei.