CCTV News:From 0: 00 a.m. on New Year’s Eve, Beijing Railway Police actively implemented security measures during the Spring Festival, organized police forces to strengthen patrol inspection and public security prevention and control work in the jurisdiction, and at the same time, dispatched police forces from the government to the big station to take up their duties, making every effort to ensure the safety and stability of the jurisdiction during the festival, ensuring the safety of railway transportation production and the safe travel of the majority of passengers.

The picture shows the police on duty in front of the ticket office of Beijing Railway Station.

　　Stick to your post to welcome the Spring Festival.

　　At 6: 30 a.m. on the first day of February 12th, Zhang Lei, a policeman from the Beijing Public Security Bureau of Beijing Railway Public Security Bureau who stayed up all night, began to patrol the carriage again. At 17: 57 on New Year’s Eve on February 11th, the T110 passenger train returned to Beijing from Shanghai, and Zhang Lei kept watch for the passengers on the train during the New Year’s Eve. On the train back to Beijing, although there were not many passengers, Zhang Lei still carefully inspected and performed his duties. In the carriage, he reminds passengers from time to time to pay attention to epidemic prevention safety and wear masks. At the same time, short-distance passengers with gifts are also reminded to check their luggage when they get off the bus to prevent them from being left on the train. When some tourists came to Beijing to inquire about the route of Beijing’s tourist spots, Zhang Lei patiently and meticulously explained and answered as much as possible to satisfy the tourists. At 10: 10, the T110 train arrived at the terminal, sent off the last passenger and checked the car body. After that, Zhang Lei’s 40-hour duty ride for the New Year ended.

　　It is understood that during the Spring Festival, in addition to organizing police forces to increase the security work in the jurisdiction, the Beijing Railway Police also dispatched more than 100 police officers from the Public Security Bureau and the Beijing Public Security Bureau to four major stations, including Beijing Railway Station, Beijing West Railway Station, Beijing South Railway Station and Beijing North Railway Station, to participate in duty tasks. At the same time, it also organized police forces from functional departments to set up a number of professional teams to comprehensively strengthen the work of cleaning up and cracking down on the jurisdiction, inventory inspection and epidemic prevention and control, and made every effort to ensure the safety and stability of the jurisdiction during the holiday season.

　　After 1 minute on the job and 60 seconds of due diligence, the Beijing Railway Police took practical actions to ensure the peace of the station area. Since the Lunar New Year’s Eve on February 11th, the security detachment of Beijing Public Security Bureau has organized the police to be on duty at Beijing Railway Station in accordance with the unified deployment of the Public Security Bureau. In the Beijing Railway Station Square, Gu Yanfeng, political commissar of the security detachment, Wang Chenguang, deputy detachment leader, and Cheng Kaijun, a policeman, were fully armed and focused. They performed their duties conscientiously and answered the inquiries of passing passengers from time to time. In Beijing West Railway Station, the Public Security Bureau organized Zhang Jun and Liu Ming, police officers of the cadre department, to be on duty at Exit 1 of the North Square of Beijing West Railway Station. While conducting the inspection of the station cars, they did not forget to patiently answer passengers’ inquiries. For those who are not familiar with the roads near the West Railway Station, they also download help through their mobile phones.

　　At Beijing South Railway Station, Wu Ge and Andy, policemen of the internal security detachment of Beijing Public Security Bureau, patrol the waiting area on the second floor of Beijing South Railway Station and remind passengers to take care of their luggage. At the underground exit of Beijing North Railway Station, policemen Wang Jinyuan, Li Yinglong and Li Zehao of the People’s Police Training Detachment of the Public Security Bureau are busy at their posts. They remind passengers carrying luggage from time to time to watch their feet and prevent themselves from tripping over too much luggage.

The picture shows the police of Fengtai station police station patrolling along the railway.

　　Night patrol line to prevent fire hazards

　　The Spring Festival in 2011 is a special Spring Festival, and the situation of epidemic prevention and control in COVID-19 is grim. the State Council called for "not returning home unless necessary during the Spring Festival" to celebrate the New Year on the spot. Considering that beijing-harbin railway City in the pipeline spans the Fifth Ring Road and the Sixth Ring Road, there are still many workers staying in Beijing for the New Year. In order to prevent someone from secretly setting off fireworks and firecrackers to ignite weeds along the railway and ensure the safety of railway transportation in the jurisdiction, from 20: 00 on New Year’s Eve on February 11th, Wang Hua, director of Shuangqiao Station Police Station of Beijing Public Security Bureau, Guo Yongzhong, political commissar, and He Ying, deputy director, led the police to patrol and inspect along the railway in the pipeline and the police station in Tongzhou Station respectively, so as to eliminate potential safety hazards in time.

　　At Tongzhou Station, Wang Hua was on duty with the police, in the checkpoint area, picking up and dropping off passenger trains. At the same time, it also sent condolences such as fruits, drinks, melon seeds and peanuts to the police on duty. On the same day, the police picked up 9 trains, 112 security passengers and 123 luggage at Tongzhou Station. At the same time, 56 people were verified by mobile police terminals. Along the beijing-harbin railway, Guo Yongzhong and He Yingdian made a patrol inspection of key sections along the beijing-harbin railway by combining car patrol and step patrol. While patrolling 17.7 kilometers to beijing-harbin railway, they found someone burning paper money 100 meters away from the railway. In order to prevent the fire caused by burning paper money, they immediately went forward to persuade the residents euphemistically and patiently, and got their understanding and support. Everyone put out the burning paper money before leaving safely. 18.6 kilometers away from beijing-harbin railway, they found that the gap of a railway fence was too large. In order to prevent other people from getting in, they promptly notified the relevant units to block it, leaving no potential safety hazard. During the period, the police of the whole institute patrolled nearly 200 kilometers in the morning, noon, evening and morning, inspected and visited 7 railway internal units, inspected 46 train bodies in freight marshalling yard, inspected 78 line equipment, and rectified one potential safety hazard in time.

　　"prospective father" who sticks to his post during the festival

　　"There are still 10 days before the expected date of delivery, when will you come back?" On February 11th, Hui Yu, the wife of the policeman Guan Nan, inquired about the news that he could go home early on WeChat. Guan Nan, the police officer of Qinghe Station Police Station of Beijing Public Security Bureau, has been conscientious and hard-working since he worked in Qinghe Station Police Station in January 2020. In just one year, he has become a leader among the young police officers in the police station and is the backbone of the police team in the police station. Because of his maturity and stability, Shi Guannan was affectionately called "Male Brother" by his colleagues who were assigned to Qinghe Station Police Station at the same time. Whether it is patrolling duty in the station area, handing over the station personnel, or investigating hidden dangers on the line, and publicizing the road protection, Shi Guannan always goes all out to complete the tasks assigned by the leaders. In the jurisdiction, in addition to working in the station area, he also visited village communities, livestock farms, dangerous goods warehouses and construction sites along the line to ensure the stability of public order in the jurisdiction.

　　The public security work is heavy, and Shi Guannan did not dare to relax. Considering that his wife gave birth after the Spring Festival, he is now a little scared. Shi Guannan took advantage of the rest time to connect with his wife by video to comfort her, so that she should not worry. After completing the security task for the Spring Festival holiday, she went back to accompany her to the hospital to give birth early. In fact, Shi Guannan knows in his heart that his promise may not be realized. Fortunately, his parents at home help him take care of his wife, which reduces his worries and buries his thoughts and guilt about his wife.

　　During the Spring Festival, there are many policemen like Shi Guannan in Beijing Public Security Bureau. They explain the responsibility and loyalty of a people’s policeman by sticking to their posts, selfless dedication and selfless work. They stick to the front line, faithfully perform their duties, go all out to protect the peace of the capital railway with practical actions, and make every effort to ensure the safety and stability of the jurisdiction during the festival.

　　Two men involved in the case were arrested at Beijing Railway Station and Beijing West Railway Station respectively.

　　At about 16: 00 on New Year’s Eve on February 11th, a man who was on the run for theft was seized in the square by the police of Beijing West Railway Station of Beijing Public Security Bureau. It is reported that the man’s name is Qi, 48 years old, from Hebei Province, and he has been handed over to the local public security organs for handling. It is also known that on February 11, a fugitive suspect wanted on the Internet for alleged theft was taken back by the Shandong provincial police. At about 17 o’clock on February 10, a fugitive man wanted by the public security organs online was arrested at Beijing Railway Station. It is reported that Wu Mou, a 33-year-old native of Shandong Province, was wanted by the police in Jinan City, Shandong Province, for alleged theft. It is reported that Wu Mou was seized at the entrance by the police of Beijing Railway Public Security Bureau Beijing Station.

　　It is reported that during the festival, in addition to maintaining the public order of major railway stations in Beijing, the Beijing Public Security Bureau of Beijing Railway Public Security Bureau also actively organized police forces to strengthen patrols and safety inspections of railway equipment and facilities along high-speed railways and important railway trunk lines in its jurisdiction, so as to eliminate potential safety hazards in time and ensure the safety of railway transportation in its jurisdiction. On February 11th, New Year’s Eve, Liu Jia, political commissar of Tongzhou West Station Police Station of Beijing Public Security Bureau, led the police to a fireworks and firecrackers discharge point near the 24-kilometer railway line of Jingcheng Line for on-site monitoring and control to prevent fire hazards along the railway line due to fireworks discharge. At 0: 00 on February 12th, the New Year’s Day arrived, and the fireworks set off reached a climax. Faced with the gorgeous night scene of flaming trees, silver flowers and a hundred flowers blooming, Liu Jia and her colleagues suddenly became wary and did not dare to relax for a moment. It was not until the morning of the first day of junior high school that they returned to the unit to have a rest after a sleepless night. (Correspondent Wang Haijiao)

Spring Festival is approaching.

Can our city set off fireworks and firecrackers during the Spring Festival this year?

How to determine the discharge time and place?

Let’s look at the local notices together.

▼

Jiaojiang

Allowable discharge time

February 9, 2024 (New Year’s Eve), February 10 (the first day of the first month) and February 24 (Lantern Festival) are all day.

No discharge area

East to Donghuan Avenue, south to Development Avenue, west to Center Avenue, and north to Yunxi Road.

Centralized discharge point

Haimen Street: the entrance square of Zhongshan Branch of Industrial and Commercial Bank of China, the parking lot in the south of Taowang Food Market, the parking lot of Baiguo Jinyue Plaza and the open space in the east of Minhui Food Market.

Baiyun Street: Jiangbin Park Qianli Haitang Monument Platform, Zhongshan Square.

Jiazhi Street: Taizhou Sports Center Square, Jiaojiang District Gymnasium Square, subgrade of the west extension section of Development Avenue (south block of Huajing Temporary House).

Huangyan

Allowable discharge time

It is allowed to be set off for 3 days, namely, New Year’s Eve (February 9), the first day of the first month (February 10) and the fifteenth day of the first month (February 24).

Forbidden range

The forbidden area in huangyan district city is Erhuan East Road in the east, Erhuan South Road in the south, Laodong South Road-century avenue-Erhuan West Road in the west and Erhuan North Road in the north.

At the same time, the following points can be considered as combustible areas in the no-burn zone:

1. South Square of Milan Hotel, Xiaodongmen, Dongcheng Street (Xiaodongmen Road-Huancheng East Road-Dongguan River);

2. Binjiang Park in Dongcheng Street (north of Jianshe Building);

3. Yongning Park in Xicheng Street (east of Yongning Happiness Science Museum);

4. Point 1, Jiangbei Park, Xicheng Street (south of Wuyue Square);

5. No.2, Jiangbei Park, Beicheng Street (west of Yongningjiang Hotel).

roads and bridges

Allowable discharge time

Fireworks and firecrackers can be set off on three days throughout the year: New Year’s Eve, the first day of the first month and the fifteenth day of the first month.

Forbidden range

East to Tailong Street, south to Xialiqiao West Road-Xin ‘an South Street-Xin ‘an West Street, west to Shangcheng Street, and north to Luqiao Avenue.

Linhai

Allowable discharge time

The day before Lunar New Year’s Eve, New Year’s Eve, the first day of the first month, the seventh day of the first month, the eighth day of the first month, the ninth day of the first month, the fourteenth day of the first month and the fifteenth day of the first month.

Forbidden discharge range

Wenling

Allowable discharge time

Lunar New Year’s Eve, the first day of the first month, the third day of the first month, the fourth day of the first month, the eighth day of the first month and the fifteenth day of the first month, totaling 6 days.

Forbidden range

Taiping Street, Chengdong Street, Chengxi Street and Hengfeng Street are areas where the sale and discharge of fireworks and firecrackers are prohibited, and fireworks and firecrackers can be set off in other specified places.

Yuhuan

Allowable discharge time

From 0: 00 on December 24th (February 3rd) of the lunar calendar to 24: 00 on the 15th of the first lunar month (February 24th) of the following year.

Forbidden range

Fireworks and firecrackers are prohibited in cultural relics protection units, transportation hubs such as stations and docks, production and storage units of inflammable and explosive materials, medical institutions, schools at all levels, nursing homes, forest fire prevention zones, power transmission and transformation facilities safety protection zones, party and government organs at all levels, institutions and other places.

balcony

Allowable discharge time

In the restricted area, fireworks and firecrackers are allowed to be set off on the day before Lunar New Year’s Eve, the day of Lunar New Year’s Eve, the first day of the first month, the fourteenth day of the first month and the eighteenth day of the first month, and all other times are prohibited.

Forbidden range

The restricted discharge areas in Tiantai City are: Luoxi, Shifeng Sixth Bridge and Eyuan in the east, New National Highway 104 and New Provincial Highway 62 in the south (at the traffic lights of Gangtou in Tang and Song Dynasties), Xiakeshan Village (Yongchang Road) in the west, and Sanmaoxi and Hanshan Road in the north (the chengguan section of New Provincial Highway 60, including Tiandu Garden and Xiushui Villa).

Xianju

Allowable discharge time

The day before New Year’s Eve, New Year’s Eve, the first day of the first month, the eighth day of the first month, the fourteenth day of the first month and the fifteenth day of the first month.

Forbidden range

Xianju City: Crossing Chengbei Road-Crossing Chengzhong Road-Huancheng South Road-Anzhou North Road-Chengbei West Road-Taihe North Road-Huancheng North Road.

Hengxi Town: the area surrounded by Linshi Line-Yong ‘an Road-Dongxi Street-Zhongxin Road.

sanmen

No sale and no release time

No sale and no release area Since January 17, 2024, fireworks and firecrackers have been banned for the whole year.

Forbidden range

Densely populated areas: Panlong Park, Xinhu Park and Xishan Park;

Offices of state organs, cultural relics protection units, key fire prevention areas such as mountains and forests, medical institutions, kindergartens, schools, pension institutions, libraries and other places determined and announced by the county government.

Taizhou Bay New Area

Allowable discharge time

February 9 (New Year’s Eve), February 10 (Spring Festival) and February 24 (Lantern Festival) are all day.

Centralized fixed-point discharge

Haihong Street Discharge Point: 50 meters northwest of Woz, Zhejiang (Ankang Road West).

The streets within the scope of non-built areas shall be stipulated by themselves in accordance with the spirit of urban meetings.

50 meters northwest of Woz, Zhejiang (Ankang Road West)

In addition, it should be noted that

The following places in the city and within 100 meters

Are forbidden to burn.

▼

It is forbidden to set off fireworks and firecrackers in the following places and within 100 meters:

(a) the office of state organs;

(two) cultural relics protection units, cultural relics protection points, historical and cultural blocks, historical buildings protection scope;

(3) Units that produce, manage and store inflammable and explosive articles;

(4) the location of military facilities;

(five) key fire prevention areas such as forests;

(6) Medical institutions, kindergartens, schools, institutions for the aged, libraries, archives, museums and places for religious activities;

(seven) in the safety protection zone of power transmission and transformation facilities;

(eight) stations, docks and other transportation hubs, rail transit and railway line safety protection zones;

(9) Within the airport clearance protection zone;

(10) Commodity trading markets and construction sites;

(eleven) high-rise buildings and underground buildings;

(twelve) other places determined and announced by the people’s governments of cities and counties (cities, districts).

The first explosion was successful!

2024-02-06

Free parking in the city during the Spring Festival!

2024-02-06

The smell of meat in the twelfth lunar month is a growing flavor of the year.

2024-02-05

Original title: "It is related to the discharge of fireworks and firecrackers during the Spring Festival, and notices are issued throughout Taizhou"

Read the original text

All relevant units:

　　According to the requirements of the China National Intellectual Property Administration Office’s Notice on Initiating the Recommendation of the Establishment of the Second Batch of Technology and Innovation Support Centers (TISC), and in order to thoroughly implement the spirit of the important instructions of the Supreme Leader General Secretary on forming an intellectual property public service system that will benefit the people and the people, the Beijing Intellectual Property Office is now organizing the application for the establishment of the second batch of technology and innovation support centers (TISC). The relevant matters are hereby notified as follows:

　　First, the reporting conditions

　　The subject of application is intellectual property information service institutions engaged in the fields of patents, trademarks, geographical indications and designs, including social information service institutions such as universities, scientific research institutions, public libraries, scientific and technological intelligence agencies, industry organizations, productivity promotion institutions in industrial parks, and various legal entities such as public service institutions of intellectual property systems at all levels. An institution that meets the basic conditions stipulated in Article 6 of the Implementation Measures for the Construction of Technology and Innovation Support Center (TISC) (Guo Zhi Ban Fa Fu Zi [2019] No.27), and can carry out relevant work or play a supporting role in promoting the transformation and application of innovation achievements, promoting intellectual property pledge financing, promoting strong chain efficiency in key industries, cultivating and popularizing patent-intensive products, supporting national strategic scientific and technological research, guiding enterprises to defend their rights overseas and early warning of infringement, etc.

　　According to the public welfare orientation and nature of TISC, market-oriented information service institutions that only provide commercial services are not recommended; Do not repeatedly recommend institutions that have been approved to become national intellectual property information service centers in colleges and universities. Institutions that have filed national public service outlets for intellectual property information are given priority under the same conditions.

　　Second, the declaration and audit procedures

　　All reporting units fill in the application materials and submit them to the Beijing Intellectual Property Office. The Beijing Intellectual Property Office will carefully examine the submitted materials, and in principle, recommend no more than five local units with good basic conditions and strong service capabilities as the second batch of TISC recommendation candidate institutions in the second phase and submit them to China National Intellectual Property Administration.

　　China National Intellectual Property Administration will review the application materials in accordance with the established procedures, organize expert review, and conduct field research as needed. Finally, China National Intellectual Property Administration and WIPO will jointly determine the list of the second batch of TISC preparation organizations in the second phase and publish it on the official website.

　　Third, the reporting requirements

　　Please fill in the Recommendation Form for the Establishment of Technology and Innovation Support Center (TISC) (see attachment) carefully, and ensure that the contents are true, accurate and complete, and submit it to the mailbox of International Exchange and Cooperation Office of Beijing Intellectual Property Office (guojichu@zscqj.beijing.gov.cn) before closing on March 22nd. If it is recommended after examination, the Municipal Intellectual Property Office shall notify the recommended unit to enter all information items in the recommendation form through the public service management system of the National Intellectual Property Public Service Network (https://ggfw.cnipa.gov.cn/gl/), and submit the sealed PDF version and the electronic WORD version of the recommendation form.

　　I hereby inform you.

Beijing Intellectual Property Office　　　　

March 18th, 2024　　

　　(Contact: Yang Qi; Tel: 55536355)

This article comes from WeChat WeChat official account:Eight o’clock news (id: healthinsight), author: ChenGuangjing, original title: "Multinational pharmaceutical companies in China for 40 years: from super-national treatment to ordinary players", the first picture comes from: vision china

For more than 40 years, multinational pharmaceutical companies have attracted countless amounts of money by virtue of China’s policy bonus and the environment where they have little power to compete with it.

In the running-in of multinational pharmaceutical companies and China’s characteristic market economy for more than 40 years, it has gone through the process from the initial foreign monks who can recite scriptures, to disenchantment, to checks and balances, and then to adjustment and discovery of new modes of getting along.

Objectively speaking, multinational pharmaceutical companies have contributed to the development of China’s pharmaceutical industry, and they have participated in creating the second largest pharmaceutical consumption market in the world.

However, they have enjoyed "super-national treatment" in China for a long time, including independent pricing and tax concessions.It has also brought many problems, including the intensification of overcapacity at the industrial end; The drug price in the public remains high, and patients can’t afford drugs.With the rise of local pharmaceutical companies, it is almost inevitable that their aura will recede.

The rise and fall of multinational pharmaceutical companies in China perfectly fits the development course of the whole pharmaceutical industry in China. So,The road taken by multinational pharmaceutical companies in China is almost a history of the development and policy changes of China’s pharmaceutical industry.

First, the first encounter: the introduction of more than just funds.

In 1978, China Pharmaceutical gross industrial output value was 7.3 billion yuan, which may not even be comparable to the revenue of a pharmaceutical company Pfizer-in the 1970s, Pfizer’s annual revenue was 1 billion dollars.

At that time, the pharmaceutical industry in China was in the stage of stumbling, and competitive domestic enterprises did not exist. There were only more than 500 kinds of drugs that hospitals could use daily.

Later, Yangzijiang Pharmaceutical, which claimed to have an annual income of 100 billion yuan, was still an unknown small factory in the town; Lianyungang Pharmaceutical, the predecessor of Hengrui, is still making hemostatic and disinfectant, and Sun Piaoyang, the technician who changed its fate, was not assigned here until four years later.

At first, foreign pharmaceutical companies were introduced, not for new drugs, but to introduce a large infusion model production line that meets the standards and can be sold all over the world.

The first foreign pharmaceutical company to enter China was Otsuka Pharmaceutical Co., Ltd.. It was signed in 1980 and put into production in 1984. By the end of 1980s, Otsuka, China had been able to produce 8 kinds of injections, which were supplied to big hospitals in Beijing, Shanghai, Tianjin and other cities, and also sold to Japan, with a double-digit increase in production capacity, sales volume and profit.

Otsuka, China, made a good start, and a large number of multinational pharmaceutical companies began to tentatively enter China.What they value has also developed from China’s industrial policy, preferential tax, low cost and labor to China’s huge market.

According to Medicine World, China joined the World Trade Organization as of December 2001.（WTO）The number of foreign-funded pharmaceutical enterprises in China has reached about 1790. The top 20 pharmaceutical companies in the world have invested and set up factories in China. In terms of market share, these enterprises account for half of the pharmaceutical market in China.

More important than market share,From production to sales, these foreign pharmaceutical companies have almost reconstructed the pharmaceutical industry in China.

Foreign-funded pharmaceutical companies not only brought more funds, mature technologies, brand-new concepts and management models, and more available new drugs to the pharmaceutical industry in China, but also brought the mainstream sales model in the pharmaceutical field at that time-academic marketing, and a new profession-pharmaceutical representative.

By 2016, China has more than 3 million medical representatives, supporting a huge sales system with a scale of 2 trillion drugs, serving 12,000 public hospitals in China.

In 1980s in China, under the strict planned economy system, pharmaceutical companies completed their production as planned, and then they were purchased by local pharmaceutical companies for unified deployment.

Pharmaceutical companies do not need to face the terminal market directly, and no one knows how to sell drugs in the modern pharmaceutical industry.

The pharmaceutical industry in Europe and America, after experiencing the rapid expansion and fierce competition after World War II, has long understood the key to the commercialization of medicine-doctors with prescription rights are the real customers of pharmaceutical companies, and the sales model for doctors is the truly effective modern pharmaceutical sales model.

Established in 1985, Xi ‘an Jansen introduced Jansen’s staff training mechanism and built the first pharmaceutical sales team in China, which is known as the "Whampoa Military Academy" in China’s pharmaceutical industry.(See:The 30-year ups and downs of China medical representatives.).

Most of these first-generation medical representatives employed by foreign-funded pharmaceutical companies have professional backgrounds, have access to first-hand scientific research materials, and were respected by doctors in the early days.

However, the situation changed quickly, and some domestic pharmaceutical companies quickly grasped the essence of pharmaceutical marketing and alienated it, resulting in sales with gold and kickbacks-hidden transactions.(doctor’s rebate+public relations rent-seeking)The cost once soared to 60% of the drug price.(See:China Medicine Changed the Past.).

Under the pressure of sales, foreign pharmaceutical companies have also begun to adopt a more subtle way of bribing doctors, as foreign media mentioned in a report in 2013: "Persuade with cash, gifts, vacations and other benefits.(medical staff)Write more prescriptions. "

All these will lay the foundation for a huge bribery case that is almost comparable to Waterloo, China, a multinational pharmaceutical company.

Second, localization: the rapid development of golden decade

In 2001, China officially joined the WTO.(World Trade Organization)China’s reform and opening up has deepened its integration with the world economic system.

Under the expectation of opening up to China and the expectation of the vast market, multinational pharmaceutical companies began to "settle down" frequently.

According to the later analysis of the industry, this process is to compete for the market, but also a confession meeting to show confidence in the China market. The giants scrambled to present "warlords" by investing in the establishment of R&D centers and factories.

After January 2002, more than 10 giants such as Novo Nordisk, AstraZeneca, Roche, Takeda, Pfizer, GSK and AbbVie also set up R&D centers in China. Lilly Asia Venture Capital Fund has also targeted the China market, with an initial investment of US$ 10 million, and plans to invest US$ 100 million in drug research and development capacity in China within five years.

According to industry statistics, by 2016, these multinational pharmaceutical companies have spent more than 8 billion yuan just to set up research centers in China.

Different from the new construction in the field of research and development, the "falling" in the field of production and sales is more like a game of "greedy snake".

In 2000, Pfizer won the largest acquisition in the history of the pharmaceutical industry with a sum of 90 billion US dollars, acquired its research and development company Warner-Lambert, and put Atorvastatin.(trade name Lipitor)In the pocket, thus surpassing Merck, the former overlord, and ranking first in the pharmaceutical revenue list. This also triggered a wave of mergers and acquisitions

This "snake-eating" game also extended to China. On July 2, 2008, after nearly two years’ efforts, Bayer finally completed the necessary regulatory approval and bought Dongsheng Technology’s "White Plus Black" and other anti-cold and cough products for 1.072 billion yuan.This also opened the prelude for multinational pharmaceutical companies to merge with China pharmaceutical companies.

Second year(2009)In the first half of the year alone, at least seven multinational giants announced the expansion of factories and production lines or the news of mergers and acquisitions and joint ventures. In the 2010s, the momentum became stronger and stronger. Merck, Pfizer, Sanofi, GlaxoSmithKline, Novartis, etc. joined in one after another. Among them, Sanofi bought the local pharmaceutical company Meihua Sunstone Group and bought a high price of over 520 million US dollars, which was the largest merger in China at that time.

Correspondingly, during the critical period of attracting investment in China, multinational pharmaceutical companies almost enjoyed the "super-national treatment" in policy.

Among them, mainly including tax incentives; Independent pricing, filing system, etc. Among all these "treatments", the most "useful" is the right of independent pricing.

Before the government pricing of most drugs was officially cancelled in 2015, only exclusive varieties could be priced independently. However, multinational pharmaceutical companies often introduce patented drugs into China, which can set higher prices.

This makes these drugs form a "scissors gap" with domestic drugs.

During this period, the scale of China pharmaceutical market has been greatly expanded. The output value of the top 100 pharmaceutical enterprises exceeds 300 billion yuan, but the concentration is less than 35%. The enterprises are "small, scattered and chaotic", and the product quality cannot be compared with imported drugs, let alone replaced. In order to compete for the market, a unique marketing model with gold sales was formed, and "emphasizing sales and neglecting research and development" began to become the mainstream of market competition during that time.

The market mechanism fails in the medical field, and the higher the drug price, the more room for operation. This is even more powerful for multinational pharmaceutical companies.Imported drugs occupy the commanding heights of the pharmaceutical market. And this advantage is more and more obvious after the patented drugs have passed the protection period.

Before and after 2006, the former director of National Medical Products Administration, Zheng Xiaoyu, was sentenced to death. As a warning, the whole drug supervision system overcompensated the behavior of rent-seeking and approving homogenized "new drugs". The drug review and approval in China was tightened rapidly, and the approval speed of domestic generic drugs was slow, resulting in a serious backlog.

In the pharmaceutical market of China, the price of drugs that have passed the patent period has started to remain high, and the gap with domestic generic drugs continues to widen.

According to some data, by 2013, the ratio of the original research drug of ceftriaxone to the retail price of generic drugs has expanded from the previous 6.25: 1 to 9.35: 1. One product and two regulations in the hospital have also become an imported product and a domestic medicine.

Many "life-saving drugs" with high technical barriers even have the highest situation in the world. For example, Gleevec of Novartis entered the mainland market of China in 2002, and the price per box was as high as 25,800 yuan. Since then, the price has remained basically stable, and by 2014 it has been much higher than 17,000 yuan in Hong Kong, China and 13,600 yuan in the United States.

Under the disparity of strength and weakness, multinational pharmaceutical companies have gradually entered the golden age of "lying down to make money" in China.

In order to further expand their advantages, multinational pharmaceutical companies also strive to expand their sales teams.

According to a paper published by Yale Law School scholars in 2014, the top 10 pharmaceutical companies in the world employ about 25,000 sales teams in China. According to IMS statistics, multinational giants such as Pfizer, Bayer and AstraZeneca have more than 2,000 first-line medical representatives, and there is a trend of further expansion.

According to statistics, the pharmaceutical market in China achieved a compound annual growth of 25% in the decade after 2000, and the income of multinational pharmaceutical companies also rocketed. AstraZeneca, for example, has built a factory in China for four years, and its sales revenue has exceeded 1 billion yuan, which is called the "dream team" of multinational pharmaceutical companies. Although other pharmaceutical companies do not have more data to prove it, they can also see clues from the grand annual meeting.

After Pfizer acquired Wyeth in 2010, an annual meeting in Dongguan, Guangdong Province cost 30 million yuan and more than 5,000 employees participated. At that time, it was called the "annual meeting of the best company". Previously, Bayer led more than 1,600 employees to carnival in Jeju Island, South Korea for 6 days, and the industry analysis cost will not be less than 30 million yuan.For a long time, the annual meeting of multinational pharmaceutical companies in China is an event that attracts the attention of the industry.

It was a prosperous time for multinational giants to develop rapidly. However, in the carnival, no one noticed the hidden worries that might make their "aura" recede.

Third, the blow: loss of supranational status

In 2013, GSK was fined a sky-high price for bribery in China, several senior executives were sentenced and one foreign executive was deported.

For a long time before GSK bribery case, multinational pharmaceutical companies were often regarded as synonymous with professionalism and compliance because of their "halo" in China market.

Until 2004, foreign media published an article exposing the "kickback shady" of pharmaceutical giants.People suddenly discovered that some so-called "standards", "rules" and "international practices", which people take for granted as reasonable behaviors, such as traveling and lecture fees, also have the risk of interest transfer.

However, in the process of law enforcement since then, due to hidden methods and insufficient legislation in China, regulators have not made a clear statement on these behaviors.

After GSK’s bribery case in China was exposed, people suddenly understood that the localization of multinational pharmaceutical companies has extended to the field of sales with gold, and the amount is so huge.

According to public information: GSK(China)In order to increase sales, a large number of salespeople were recruited and paid bribes to medical staff in medical institutions all over the country. Travel expenses, lecture fees, organizing tours, etc. are all ways to expand the use of drugs or expand their use. Only after 2007, GSK, like more than 700 travel agencies and consulting companies, transferred 3 billion yuan, which was suspected to be used for "illegal fund disposal".

Since the GSK case, people have clearly realized that,China’s regulators are ready to "shoot".

In fact, multinational pharmaceutical companies entered the China market in the form of joint ventures from the beginning. Their technology is often not the latest technology. It is mentioned in Mainstream-Wisdom of the Leaders of Pharmaceutical Companies in China that the overseas direct investment theory of developed countries clearly mentions that the core technology will remain in the headquarters, and the second-rate technology and production line will flow overseas. Inadequate management, and multinational pharmaceutical companies create book losses and evade taxes by making high prices of overseas raw materials.

During this period, scholars in China also realized that we can’t catch up with the international level by introducing foreign capital to build tertiary industry.

However, in the early days of reform and opening up, China’s technology was too weak, and these mature technologies can meet the demand to a certain extent.

However, in the subsequent development, local pharmaceutical companies in China are also rising rapidly.

Today, even the world’s leading PD-1 inhibitor has become the object of research and development. According to Baiaotai’s announcement, after Bristol-Myers Squibb and Merck launched PD-1 in 2014, 85 of the 154 PD-1 in the world were developed or jointly developed by China enterprises.

Since 2018, only five domestic PD-1s in China have been approved for listing.

Under the pressure of domestic drug competition, the imported PD-1-O and K drugs, which initially cost 1 million yuan to be listed in the United States, were given the lowest price in the world as soon as they entered China. After several rounds of price wars, the annual cost continued to drop sharply.

Especially after the national medical insurance negotiations, under the offensive of price reduction of domestic drugs, although the above two imported drugs were not successfully negotiated, the annual expenses were also reduced from more than 300,000 yuan and more than 200,000 yuan to more than 100,000 yuan. The domestic PD-1 can even reduce the personal out-of-pocket expenses to 10,000 yuan.

The state-led "Major New Drug Creation" project was also launched in 2008. By 2019, there were 139 new drug certificates, 44 of which were Class I new drugs. These drugs are all "chips" in the game of medical insurance negotiation and forced price reduction of imported drugs.

Before the GSK bribery case was investigated, "domestic Iressa" Ectinib went on the market. This small molecule targeted drug with completely independent intellectual property rights in China broke the monopoly position of European and American pharmaceutical companies. In the first national negotiation in 2015, Iressa was forced to reduce the price by 55%, and the average monthly cost dropped from 12,000 yuan to about 5,500 yuan. This is not only the preface of domestic substitution of imported drugs, but also gives the competent authorities the confidence to severely punish GSK.

Nowadays, innovation has become the common choice of more and more head pharmaceutical companies. Statistics show that the total value of China’s pharmaceutical industry has been close to 3 trillion yuan by 2017. In 2019, the income from the main business of the top 100 enterprises reached 929.64 billion yuan, with a growth rate of over 10%. The average R&D cost is more than 550 million yuan.

According to Wind data, the R&D investment of A-share pharmaceutical enterprises in China was less than 10 billion yuan in 2011, and it has exceeded 50 billion yuan by 2019. Judging from the annual reports, in 2020, there will be as many as 14 R&D investments in China exceeding 1 billion yuan; The research and development of more than 40 pharmaceutical companies accounts for more than 10%.

China is increasingly emboldened to reduce the price of imported drugs. With more and more domestic innovative drugs on the market and generic drugs passing the consistency evaluation, a subversive reform is gradually taking shape.

The rules of the game have changed, and multinational pharmaceutical companies have changed from the role of "wrestling" with policy makers to ordinary players, who can only comply with the rules and compete fairly with local pharmaceutical companies.

Fourth, the Great Retreat: How many people want to go back ten years ago?

In 2017, leaving the shut-down Shanghai Lilly China R&D Center not only announced the end of an era, but also seemed to push down the first domino of foreign companies’ assets withdrawing from China.

Then Novartis dissolved the biopharmaceutical research and development team in China, and the early research and development of antibiotics and antiviral drugs was stopped, and 140 people were abolished; GSK China R&D Center was abolished, and the project under research was transferred to American research center; Novo Nordisk China R&D Center layoffs; AstraZeneca China preclinical research business divested …

Dominos continue to overwhelm more business.

In 2019, Lilly sold the rights of antibiotic varieties Xikelao and Jingkexin in Chinese mainland, as well as the production plant of Xikelao in Suzhou.

Pfizer also packaged mature products such as Lipitor and Luohuoxi into Pfizer Puqiang and eventually merged them with generic drug giant Mylan.

Since then, GSK and Novartis have also sold their factories in China. Boehringer Ingelheim stripped off the promotion of Aiquanle, Kebite, Silihua and Sihehua; Mengdi Pharmaceuticals is simply selling its business unit in China.

In 2021, more and more heavy product lines in the past were "killed with tears".

Then, a batch of drugs began to withdraw from the China market. Just three months ago.(May 24)Among the 283 cancelled approval drugs announced by National Medical Products Administration, Weijianle of AbbVie is included.(Obipali tablets), Yi Chery(Dasebvir Sodium Tablets), Li Luo of Johnson & Johnson.(Procarbidol Succinate Tablets)Cape orchid with excellent time ratio(levetiracetam tablets), Novi of Merck.(Sigliptin Phosphate).

Many of these products, such as Merck’s hypoglycemic drug Genevix, are on the track with annual sales of several billion yuan, and now it is a mixed feeling to leave.As for the strategic deployment of multinational pharmaceutical companies, some investors even ridiculed that this is the "Dunkirk" of the pharmaceutical industry.

In the past four years, the state organized the centralized procurement of medical equipment, which set off a huge wave in the pharmaceutical market in China, which was called "tsunami". Although only 218 varieties are involved at present, the market scale is 220 billion yuan, but its foreseeable influence has made people who are used to the traditional marketing to conquer the world feel insecure.

There is no room for further clinical promotion, regardless of whether the bid is won or not, because the price is cut at the waist and ankle. The traditional marketing model is facing unprecedented challenges. It is difficult for multinational pharmaceutical companies to win the bid in order to maintain global prices.

In the field of innovative drug research and development, the giants have also encountered close-knit struggles from local enterprises. The once unattainable PD-1/PD-L1 was dragged into the Red Sea by China pharmaceutical companies. From the annual cost of millions of yuan to the minimum of less than 20 thousand yuan.

Mature products are surrounded by generic drugs, new products are facing price cuts in medical insurance negotiations and rapid attacks from competitors. Multinational pharmaceutical companies are in a crisis of being besieged on all sides.

In order to maintain their advantages and seek new growth points, in addition to divesting "non-core business", the adjustment and breakthrough of multinational pharmaceutical companies have never stopped.

In January 2019, the distance from cardiovascular heavy drugs was "determinable"(Chemical name: rosuvastatin)Just two months after losing the bid in the 4+7 pilot project, AstraZeneca, which is known as the "dream team", threw a heavy news: it has obtained the exclusive promotion right of Xuezhikang in Chinese mainland from the Green Leaf Group.

Multinational pharmaceutical companies sell proprietary Chinese medicines, which breaks through the inherent cognition of the industry. What breaks the industry cognition even more is that it has also started CSO.(Contract Sales Organization), "big package business".

A year later, AstraZeneca accepted the exclusive promotion right of a medical-grade home twelve-lead ECG instrument in China. According to the medical economic news, the company will also package 100 products-50 domestic or imported agent products and 50 diagnostic equipment products.

The sales cooperation between domestic pharmaceutical companies and multinational pharmaceutical companies is getting closer and closer, and the industry is beginning to be surprised by this treatment. Even Pfizer, once a "big pharmaceutical factory in the universe", has come to an end.

Not long ago, Cao Junyang, vice president and chief medical officer of Pfizer China, also revealed in an exclusive interview with the medical profession that apart from speeding up the introduction of self-developed products into China, Pfizer will also cooperate with local enterprises or multinational enterprises to give full play to its "leading commercialization advantage in the pharmaceutical field in China".

Simply understand, that is, to give play to its advantages in the sales field.

With the accumulation of sales teams in the past decades, the choice of multinational pharmaceutical companies is unexpected, but it is reasonable.

With the aging and high incidence of cancer, the pharmaceutical market in China has maintained a high-speed growth all the year round. Foresight Industry Research Institute predicts that by 2025, with its growth rate of 14% to 17%, it will exceed 5 trillion yuan.

Such a "big cake" can’t be eaten without sincerity, and multinational pharmaceutical companies are also trying their best.

From 1980 to 2021, the scale of the pharmaceutical market in China increased from less than 8 billion yuan to nearly 3 trillion yuan.

Can multinational pharmaceutical companies that have lost their "aura" subvert their profit model for 40 years in a brand-new pattern and rules and find a new way in this trillion-dollar market?

References:

Introduction, for digestion and absorption-Notes on an interview with China Otsuka Pharmaceutical Co., Ltd., Cong Yu.

"Creating a New Management Situation by Producing World-class Products —— An Interview with China Otsuka Pharmaceutical Co., Ltd.", Zhang Zhitao.

Mainstream-the Wisdom of China Pharmaceutical Leaders, Tao Jianhong, Tan Yong.

The Impact of Foreign Capital Utilization on China’s Pharmaceutical Industry, Liu Xue, Chen Wenxuan, etc.

The investment mind of multinational pharmaceutical companies has changed, He Rong.

This article comes from WeChat WeChat official account:Eight o’clock news (id: healthinsight), Author: Chen Guangjing

With the recent official statements on optimizing and adjusting the real estate policy, a new round of stabilizing the property market has revived. The analysis generally believes that the signal that the current "policy bottom" is once again solid is obvious.

However, in the process of great changes in the relationship between supply and demand, it is particularly important to judge the boundaries and trends of policy easing. In the attempt to adjust and explore, many cities first gave a relatively safe way of encouragement-housing subsidies.

Data map: There are many high-rise buildings in the city. China News Service reporter Wang Dongming photo

Two provincial capitals increased subsidies.

On August 4th, according to the official micro-signal "Nanjing Real Estate Micro-government" of Nanjing Housing Security and Real Estate Bureau, Nanjing issued the notice of "Further Optimizing Policy Measures to Promote the Stable and Healthy Development of Nanjing Real Estate Market". The first of the eight policies is the implementation subsidy for purchasing new commercial housing.

Specifically, the new six districts are encouraged to continue to give a certain proportion of housing subsidies to those who buy new commercial housing within the specified period according to the actual regional market, and Qixia District and Yuhuatai District will give subsidies to the purchase of new commercial housing after evaluation based on the actual market within their respective jurisdictions, so as to effectively reduce the burden of rigid and improved housing purchase.

Zhao Qian, a senior analyst at the Central Finger Research Institute, pointed out that as early as 2022, several suburban areas in Nanjing, such as Liuhe, Lishui and Gaochun, had already implemented a series of subsidy policies. This official document, in addition to re-emphasizing that the new six districts can continue to implement housing subsidies, mentioned the new regulations for Qixia and Yuhuatai for the first time.

"This is also a policy put forward by Nanjing after comprehensively studying the buyers in various regional markets. Later, each district will introduce specific implementation details, and the implementation effect remains to be seen." Zhao Wei said.

Nanjing has also become the second provincial capital city to join in this round of property market adjustment. Just the day before the introduction of the New Deal, Zhengzhou issued 15 policies to regulate the property market, which also put the content of housing subsidies at the forefront, including subsidies for young talents to buy houses, families with many children to buy houses, and deed tax on housing purchases.

"Zhengzhou has a total of 15 policies, and 3 of them all mention various subsidies, which fully shows that in this round of property market boosting work, financial subsidies and other tools will be actively used, reflecting the new orientation of the current housing purchase policy." Yan Yuejin, research director of Yiju Research Institute, said.

　　Data Map: Painting boats swim on Qinhuai River in Nanjing, Jiangsu. China News Service reporter Li Bo photo

What is the thrust of the "icing on the cake" policy?

Following Politburo meeting of the Chinese Communist Party’s "timely adjustment and optimization of real estate policy" on July 24th, and the Ministry of Housing and Urban-Rural Development followed closely to clarify the direction of policy support, many places quickly launched actions to release policies related to stabilizing the property market, and the content related to housing subsidies also became hot.

On August 4th, Ganzhou, Jiangxi Province issued 18 real estate measures, which mentioned supporting the implementation of house purchase subsidies and continuing to implement phased house purchase deed tax subsidies. On August 1st, Jiangsu Jurong introduced a new policy to stabilize the property market, including deed tax subsidies for families with many children to buy new houses and deed tax subsidies for new commercial housing. On the same day, Sichuan Ya ‘an Economic and Technological Development Zone issued a new policy to stabilize the property market, and proposed to buy new houses to subsidize the purchase of houses, including subsidies for talents and families with many children.

"The biggest feeling is that although I spent a lot of money to buy a house before, I still feel like I am getting a subsidy." Citizen Xiao Miao (pseudonym) bought a new house in July this year, and after paying the deed tax, she applied for a subsidy for talents to buy a house. She received a short message one week after the application, and the money arrived less than half an hour later.

On social platforms, more and more people share their experience of applying for housing subsidies like Xiao Miao. At present, granting housing subsidies is one of the important means for cities to support housing consumption, and the frequency and proportion of policies remain high.

According to the statistics of the Central Finger Research Institute, in the first half of 2023, more than 50 cities have implemented the housing subsidy policy. The subsidy methods mainly include one-time subsidies according to sets or areas, one-time or phased payment of deed tax subsidies, payment of consumer vouchers subsidies, talent housing subsidies, and a certain proportion of housing price subsidies.

"In the short term, it is expected that the demand-side policy will still focus on reducing the threshold and cost of buying a house. The’ one district, one policy’ and the combination of the birth policy are important directions, and the credit policy for improving housing demand is also expected to increase." Chen Wenjing, director of market research at the Central Finger Research Institute, said.

However, there are also voices that housing subsidies tend to be short-term encouragement and assistance, and cannot really become a decisive factor affecting property buyers. The White Paper on House Purchase Intention in 2023 published by Leju. com shows that tax adjustment and house purchase subsidy have little influence on decision-making. In the choice of "which of the following changes will affect your decision to buy a house", "tax/interest rate will continue to decrease" and "large house purchase subsidy" can only affect 4.81% and 11.12% of buyers.

"Judging from the current relaxed environment of the property market as a whole, most of the housing subsidies in various places are part of the’ combination boxing’ of local regulation and relaxation." Zhang Bo, president of 58 Anjuke Research Institute, previously commented on the housing subsidy policy, saying that the effectiveness of a single policy on market release is relatively limited, and it needs to form a joint force with other regulatory relaxation policies, which will have a certain influence on the market.

The original Wei Yiyi three cooks

Recently, the pork stocks in hand have gone up a lot, but they are both happy and worrying.

Last year, when the price of pork was the highest, I ate a lot of cheap imported pork.

For imported pork, many people in Chinese still have bad feelings.

In addition to the epidemic factors, frozen meat makes people feel stale.

Of course, the most important thing is that many people think that imported pork has a peculiar smell. Some people say it is smelly, while others say it is coquettish.

The reason is that there is a saying that it is caused by killing pigs abroad without bleeding. Is this true?

01

In fact, all the serious pigs in the world are bleeding.

There is a long-standing saying that when pigs are killed abroad, they are electrocuted or suffocated with carbon dioxide, and then they are decomposed and cut without bloodletting, so pork has an odor.

And many of Chinese’s impressions of killing pigs are probably still indigenous methods: forcing pigs into a corner in a pigsty, tying up four hooves on their backs, and the pig butcher sealing his throat with a knife, bleeding all over the sky …

I have to say, both of these statements or impressions have some imaginary elements.

It is not impossible to kill pigs by indigenous methods, but the scene is too bloody and inefficient.

Killing pigs in slaughterhouses in China is actually similar to that in foreign countries. Electric shock or suffocation causes pigs to lose consciousness and then slaughter them.

Moreover, no matter in China or abroad, the slaughtered animals will bleed, so there is no problem of bloodletting.

If you don’t bleed after slaughter, the meat will rot more easily, and blood stasis will form on the surface, which will affect the beauty of the meat.

And what we usually eat, whether it is hot fresh meat or cold and sour meat, is spared blood.

Especially the meat with acid discharge, should be kept at 0℃-4℃ for 12-24 hours after slaughter.

On the one hand, it drained the blood and body fluids, on the other hand, the low temperature also inhibited the growth of bacteria, and the protein in the meat also changed, making the meat more tender.

Imported frozen meat is basically pre-acidified. However, the taste and flavor of frozen meat will indeed decline.

But if you say that smell, it’s really not because you didn’t bleed.

02

What is the real source of pork odor?

The unpleasant taste of pork is actually a kind of smell called Boartant.

The literal meaning is obvious. Some pork is stinky or coquettish, and its main source is boar pork.

Because boars contain high concentrations of androstenone and dung odor.

Androstenone is a male hormone and smells like urine. When boars grow up, the content of androstenone in their bodies will be very high, and even the saliva will smell of androstenone. There is no androstenone in sows, but the content is much lower.

Fecal odor is a substance that smells like poop. Generally speaking, the intestines of mammals contain fecal odor, and pigs are no exception. Pig dung odor is mainly produced in the large intestine, so you should pay attention to it when cooking well.

A part of the fecal odor will be excreted casually, and the other part will be absorbed into the body by the intestine and then decomposed by the liver.

However, there is an ultra-high concentration of steroids in boars, which will prevent the liver from decomposing fecal odor, so the undecomposed fecal odor will gather in boars’ fat and produce an odor.

However, most of the domestic pork we buy does not have this odor. Why do some imported pork have it? Is it unscientific to eat all sows in China?

In fact, both pork farmers and manufacturers want to try their best to remove the odor of boars. After all, no one will like it.

The most traditional way to get rid of the odor of boars is castration, which is also called knocking pigs in many places.

Because androstenone is produced in the testicles of boars when they are sexually mature, the steroid that prevents the decomposition of fecal odor is also a kind of testosterone.

Therefore, it is a common practice in China to castrate boars when they are very young, except for keeping breeding pigs. And sows, except those with piglets, were also slaughtered when they weighed about 100 kilograms.

Well, since castration can completely solve the problem, why don’t foreign countries castrate pigs? Do they like the taste?

In fact, it cannot be generalized whether foreign countries castrate pigs or not, and the situation in each country is different.

Let’s start with why some countries don’t castrate pigs.

No one likes the smell of boars, but there are two main reasons for insisting on not castrating pigs:

First, the issue of animal welfare. Some people think that castration of boars violates ethics and harms animal welfare, so castration is prohibited, and some countries require anesthesia before castration.

In 2010, the European Union requested to stop surgical castration of boars before January 1, 2018, but this goal was not achieved.

The second is the economic benefit. After castration, the feed conversion rate of boars will decrease, which is commonly known as "slow growth", and the fat content will increase, and the meat will become fatter.

Is there any way for castrated pigs to get rid of the smell of boars? Actually, there are.

A vaccine was launched around 2010, which can chemically castrate boars.

Vaccines are used to inhibit testicular function, thereby preventing the production of androstenone and steroids.

You can’t say that this vaccine has no effect at all, but in New Zealand, where this vaccine has been applied, the content of two substances that produce odor in pork is higher than the EU level.

03

What should I do if I buy smelly pork?

Although no one likes the smell of boars, they will still buy imported pork (after all, it is cheap) or accidentally buy pork with odor.

First of all, you need to do your homework before buying.

China’s main pork importers are Germany, Spain, Britain, the Netherlands, the United States, Canada, Brazil and other countries.

▲ Source: The second progress report of the European Declaration on Alternatives to Swine Surgery in 2015-2017.

Let’s talk about Europe, Spain and Britain, which have a large proportion of castrated boars, are likely to step on thunder; Some of the boars in Holland have been castrated, while more than 80% of the boars in Germany have been castrated.

In the above picture:

Red is the country that castrates less than 20% boars;

Yellow is the country where 20-80% boars are castrated;

Blue is the country where more than 80% boars are surgically castrated, but anesthesia (local/systemic) and/or long-term analgesia are used;

Green is a country that castrates more than 80% boars without anesthesia or analgesia.

In North America, the United States and Canada, there are also castrated boars, but the proportion is not so large, and there will be some restrictions on their use. It is unclear whether they will be imported to China.

▲ Import volume and proportion of major pork importing countries in China in 2018

As for Brazil, the country with the highest growth rate of China’s pork imports in the past two years, to be honest, no valid information has been seen.

If you really buy pork with bad smell, you don’t have to throw it in the trash can directly. There are still ways to save it.

The best way is to "run running water".

Wash the pork, put it in a cold water pot, fire it, and turn the fire to a minimum, so that it will almost go out.

For almost half an hour, a layer of blood foam floated on the surface, and the pork was fished out and washed with warm water. The pork treated in this way, although the skin is cooked, is still raw inside, and the odor has been removed.

In fact, to tell the truth, apart from the epidemic factors, there is nothing wrong with many imported pork except that it is not very delicious.

May we all eat more meat, eat meat well and eat good meat in the new year.

END

Wen | Wei Wei

Original title: "Imported pork has a strange smell, is it really because foreign countries kill pigs without bleeding? 》

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The original digging number is included in the topic # 44 migrant workers.

In recent weeks, I have a toothache. According to past experience, either my gums are severely atrophied or my teeth are cracked and need to be filled. So I hung up the number of a famous dental hospital in Guangzhou with my mobile phone, which was particularly difficult to hang up. It was full in recent days and I could only hang up the number four days later.

At 7 o’clock this morning, it was drizzling in the sky. I set off for the hospital, filled out a form to take a temperature measurement, and wanted to know whether the dental insurance could be reported at the registration office. I saw a buddy in front of me paying money, the first one was more than 6,700, and the second one was more than 1,900. I was so scared that I almost wanted to go home, but I wanted to come all over again. The dentistry was so profitable that I had to dig it.

At 8: 30, there were a lot of people sitting at the door. The hospital was not big, but there were departments in the elevator. I was looking at the dental pulp department.

On a whim, I want to see the flow distribution of people in various departments at this time, and I ran a circle on the upper and lower floors:

6F Children’s Stomatology: 1 person

5F Orthodontics Department: 8 people, Dental Pulp Department: 8 people.

4F Implant and Prosthetic Department: 8 people, Oral and Maxillofacial Surgery: 6 people.

1F Radiology Department: 5 people, Periodontology Department: 9 people.

(Not included in the treatment)

It’s my turn. After checking, it was concluded that a tooth needs to be filled. After paying the total fee of 305, I paid 200 medical insurance for reimbursement of 105. I just saw the expenses of various projects on the screen of the hall, and took a photo.

How to estimate the annual income of this hospital? It is known that the maximum number of doctors registered in a day is 30. From the registration applet, we can see that the number here is full almost every day, and we can see how many doctors there are in each department every day.

The number of patients per day can be calculated as follows:

Pediatric stomatology: 6 doctors *30 numbers =180 people.

Oral and Maxillofacial Surgery: 5 doctors *30 numbers =150 people

Orthodontics: 7*30=210 people

Dental and endodontic department: 9*30=270 people

Periodontal disease department: 5*30=150 people

Implant Restoration Section: 5*30=150 people

According to this number of people, the registration fee alone can earn 10 yuan *1110 people =11100 yuan per day, which is really cool!

The total income can be estimated if there is another per capita cost. My idea is to take the cost of the most common treatment items in each department instead of the per capita cost. For example, periodontal disease is tooth cleaning, and dental pulp is tooth filling. Combined with the cost photographed in the hall and online data, some common treatments, such as tooth cleaning, pulling out a wisdom tooth, applying fluoride to the whole mouth, filling a tooth, etc., cost about 500. Roughly speaking, if 500 yuan is taken as the per capita cost, then the hospital’s annual income.

500 yuan *1110 people/day *365 days = about 200 million.

This hospital is only a small branch. If it is the General Hospital, it is estimated that its income will double. According to the hospital’s WeChat WeChat official account, there are 50 doctors here, which means that each doctor brings 200 million /50=4 million in revenue every year.

With such a high per capita income, it can be inferred that the income of dentists should be high. Digging through the financial report of a dental A-share listed company, which has 21 dental hospitals in Zhejiang, there are several interesting data in the financial report:

For example, the annual revenues of the above four stomatological hospitals are 620 million, 390 million, 140 million and 40 million respectively, and the net profit margins are 40%, 28%, 28% and 16% respectively.

For example, 54.99% of the cost of stomatological hospital is labor cost, which proves the high income of dentists.

So how high is the income of dentists? I searched a lot of answers in Zhihu. The monthly salary of dentists in public hospitals in first-and second-tier cities is between 10,000 and 20,000, and 30,000 to 40,000 if they are deputy directors or above.

Data reference from: https://www.zhihu.com/question/364101818/answer/958783096

Dentists in private hospitals earn more. Here is an authoritative data, which comes from the dictation of the founder of a dentist online platform:

At present, private dental hospitals basically adopt the salary method of basic salary plus commission. The monthly income of dentists with lower income is about 20,000 to 30,000 yuan, and the monthly income of dentists with higher income can reach 60,000 to 70,000 yuan. Some top dentists will have a higher commission, and may even break 500,000 yuan a month.

As we are now, we basically recruit doctors from some good public hospitals such as Huaxi Stomatology, and the success rate is still relatively high, because in private clinics, especially brand-operated private clinics, the treatment is also better, and the recognition of doctors in the industry is not worse than that in public hospitals.

He also mentioned that there is a great demand for dentists in China:

The ratio of dentists to population is only 1: 28,000, compared with 1: 1,000 in developed countries such as the United States, 1: 2,000 in Japan and 1: 4,000 in Western Europe, which fully shows that there is a great gap in the demand for dentists in China.

Source: https://www.iyiou.com/analysis/2018052373041.

I really envy, envy and hate. The key dentist is still a profession that gets more and more popular as he gets older. He will not retire at the age of 35 like the siege lion, and he has a high sense of security!

Original title: "How much can a dental clinic earn a year? 》

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yuan

Yuan Dynasty (1206-1368)

xiao

night

jie

festival

February 26th, 2021 is the Lantern Festival, which is near the weekend. During the holidays, people and vehicles flow heavily. In order to ensure the safe and smooth road traffic during the holidays and create a good road traffic safety environment for celebrating the festival, the Traffic Management Bureau of Jilin Provincial Public Security Department issued the "Lantern Festival Two Announcements and One Prompt" in Changchun City, asking the majority of traffic participants to reasonably choose travel time, travel routes and travel modes, avoid travel peaks and easy-to-block sections, drive safely and travel safely.

Weather conditions during the Lantern Festival

During the Lantern Festival, expressways are not free. According to the "Implementation Plan for Exempting Small Bus Tolls for Major Holidays", the policy of free passage of 7-seat (including 7-seat) small bus expressways will be implemented for four national statutory holidays: Spring Festival, Tomb-Sweeping Day, Labor Day and National Day.

Prediction of traffic flow during Lantern Festival

It is estimated that the population flow in the Lantern Festival in 2021 is significantly lower than that in previous years, and there is a strong uncertainty in traffic flow. Before the holiday, the traffic flow will be relatively dispersed, and after the holiday, it will be more concentrated, and the road traffic flow in the bustling business district will increase greatly.

Traffic safety tips for Lantern Festival

1. During the Lantern Festival, family reunions with relatives and friends and short trips increase. Drivers are requested to travel at the wrong peak as much as possible. In case of traffic congestion, please obey the traffic police’s command, do not force traffic jams, and do not fight for roads.

2. Friends get together to celebrate the Lantern Festival and drink more. Drinking alcohol will lead to slow response and slow action, and the driver’s ability to control the vehicle will decrease. For the safety of you and others, please remember "drink without driving, drive without drinking!"

3. Take part in the Lantern Festival folk celebrations. Never drive or take overcrowded minivans or passenger vehicles. Never take tractors, low-speed trucks or illegally operate "black cars" to travel.

4. When driving minivans and passenger vehicles through icy wading roads, please keep driving at a constant speed, keep a distance from the vehicle in front, and do not brake suddenly to avoid side slip.

5. There are many people in tourist attractions, so drivers should pay attention to civility and courtesy, obey traffic signals, don’t make a sharp turn at intersections or narrow sections without traffic lights, and pay attention to slowing down when driving through crosswalks or intersections to avoid unnecessary traffic injuries.

6. During the festival, the traffic volume is heavy. If there is a traffic accident, please call the police in time. If there are no casualties and minor traffic accidents, you should leave the scene immediately after taking photos, and drive to an open place to negotiate or call the police for handling, so as to prevent traffic congestion or secondary accidents; If there are casualties, protect the scene, rescue them in time, and call the police immediately. Don’t be lucky enough to escape.

Expressway driving tips

First, prevent the car from being in bad condition

Before leaving the vehicle, check the vehicle and keep it in good condition.

Second, prevent improper overtaking of passing cars

Try to avoid overtaking, and when passing, the qualified party should take the initiative to stop for courtesy; At night, the lights are used to signal to ensure that they meet slowly under safe conditions.

Third, prevent turning too fast

When turning, you should slow down the speed ahead of time, hold the steering wheel steady and tap it slowly. When the line of sight is not good, turn left to the right as far as possible to expand the driving sight.

Four, prevent braking too fast

Concentrate on driving, try to use predictive braking, and make good use of the engine’s drag to slow down to avoid emergency braking.

The Lantern Festival will remain unchanged.

If you encounter an emergency on the expressway, please call the 24-hour alarm number in time: 0431-12122.

Original title: "Friendly Tips | Don’t forget traffic safety during the Lantern Festival reunion"

Read the original text

1905 movie network news　"Because the world is round, we will meet again. On the 2307th day after the film was released, Guo Gangtang and his son reunited at the end of 24 years. This is the best ending of the movie. May there be no abduction in the world and no separation in the world. "

　

On July 13th, a press conference was held in the Ministry of Public Security, and it was announced that Guo Zhen (registered as Guo Xinzhen), the prototype of the abducted child of The Lost Orphan, was successfully recovered in the "Reunion Action" and a wedding ceremony was held. After that, the producers of The Lost Orphan released a poster to wish Guo Gangtang and his son a reunion. Lei Zekuan, who plays in the film, also specially recorded videos to express his wishes for the reunion of prototype Guo Gangtang and his son.

Andy Lau said, "Through this lens, I hope to tell Brother Guo that I admire your persistence and pay tribute to the efforts of the public security organs for many years. Here, I appeal to all my friends to join me in supporting the anti-trafficking work and hope that more separated families can reunite as soon as possible. "

In response to this incident, 1905 Film Network contacted the director exclusively at the first time.Peng SanyuanShe revealed that after the news of finding her son in Guo Gangtang was announced, she immediately contacted Guo Gangtang and told Andy Lau. Guo Gangtang replied to her, "Elder sister, I can live a normal life now", and Andy Lau at work quickly replied to her with a smiling face and a prayer gesture expression with his hands folded, very excited.

"Guo Zhen, you may be a little confused about the sudden appearance of your biological father, and you don’t know what to do, but you can learn about your father Guo Gangtang’s 24-year journey through many channels, and every step is love for you, so I wish his appearance is not a burden to you, only love itself!" While posting a message of blessing on the Internet, Peng Sanyuan hoped that Guo Zhen would not have too much psychological burden in the face of his biological father.

　

"I want to say to Guo Zhen, don’t have psychological burden, because for him, Guo Gangtang actually came to him with love 20 years late and blessings from many people." "Don’t think too much, just accept such a late love."Peng Sanyuan believed that Guo Gangtang had been psychologically prepared, because he had said in an interview that he would get along with Guo Zhen’s adoptive parents like relatives, and Guo Zhen’s heart would certainly be shaken, so he didn’t want to be affected too much and change his original life track.

　

Recalling the creative process of "Lonely Lost", Peng Sanyuan said that she began to pay attention to the group of abducted children after seeing the relevant reports of Guo Gangtang in 2010, and contacted the Baby Home Public Welfare Website and the Ministry of Public Security’s Abduction Office successively to track the whole situation of abducted children, and started to create this film after a lot of interviews.

　

The ending of Lost Orphan is that Lei Zekuan, the protagonist, embarks on a straight road and continues his difficult journey of finding relatives. Now prototype father and son finally get together, Peng Sanyuan said frankly:This is the real ending of the movie we expected at that time. We don’t want this father to be on the road forever.

The following is an interview record:

　

1905 Movie Network: Have you contacted the parties after you learned about this matter?

　

Peng Sanyuan:Because we have always had a group in Lost Orphan, including Guo Gangtang, and it is in this group that I posted. I told Gangtang that I was very happy, because he was probably very busy the other day. After he made an appointment, he sent me a short message. He said, Sister, I can live a normal life now.

　

1905 Movie Network: How did you reply?

　

Peng Sanyuan:I have 10,000 joys and 10,000 blessings. I really hope that he can return to a normal life track as soon as possible, live a normal life, and stop running around and suffering.

　

1905 Movie Network: After hearing that you knew about this matter, you contacted Andy Lau at the first time.

　

Peng Sanyuan:Yes, I didn’t tell Brother Hua until Guo Gangtang released the news to the media. I sent him a message. I said that the son of the prototype character of Lonely Lost had been found. He quickly gave me a smiling face and then a gesture of prayer. I guess he might be working at that time.

1905 Movie Network: You wrote an article in Weibo, which was not only a blessing to Guo’s father, but also some words to his son. Why do you think so?

　

Peng Sanyuan:Because Guo Gangtang is psychologically prepared for this matter, and Guo Gangtang has been running for more than 20 years, he is always looking forward to the day when he meets his son, so Guo Gangtang doesn’t need psychological construction, but Guo Zhen is different. He was originally in his own normal growth trajectory, and he didn’t know that he was abducted, so the sudden appearance of this matter should be a shock to him. The reason why he didn’t know, adoptive parents must have never told him that he wasn’t his own. If he had, he would have looked for him. Since he didn’t know, this matter would have been very shocking to him.

　

It takes a psychological time for him to accept Guo Gangtang, so I want to tell Guo Zhen not to have psychological burden, because for him, Guo Gangtang actually came to his side with love that was 20 years late and many people’s blessings. Don’t think too much about whether he should return to his biological parents’ home and how to treat his adoptive parents. I don’t think this should be his psychological burden. He just needs to accept such a late love.

　

I think both Guo Gangtang and Guo Gangtang’s family are wise enough to gradually establish parent-child relationship with their children and get along with their adoptive parents as relatives in the future. Because in previous interviews, Guo Gangtang once said that if he found a child, he hoped to get along with his adoptive parents like relatives. Therefore, Guo Gangtang is prepared, while Guo Zhen is not. I hope he can have a relatively normal life track under such a shocking situation and not change his life track.

1905 Movie Network: We saw Andy Lau,When the main creators sent their blessings, the film also sent a reunion poster. Is there anything different in your heart?

　

Peng Sanyuan:I was particularly moved. This is the real ending we expected at that time. We don’t want this father to be on the road forever. Because our original movie ending gave him a straight way forward, a relatively bright way, and gave him a vision. As the master said, if you do more good deeds, you will meet each other when you get together.

　

Because we can’t answer this question, when can he find Guo Zhen and when can he find his son?In 2037 days after the release of our film, they finally met, or by the efforts of the public security department, the happy ending was realized. For us filmmakers, this ending should be a real ending.

　

1905 Movie Network: From the director’s point of view, does this matter have any influence on your future creation?

　

Peng Sanyuan:I hope that each of our works can help and contribute a little to the society. No matter from which angle, it can promote the progress of the society and the kindness and beauty of the people. We still hope to do something for the society through our own artistic creation, and this original intention will not change.

[Network+] China basketball finally won the first world championship in adult competition! In the women’s final of the 2019 FIBA Three-Man Basketball World Cup held in the early morning of 24th, the China women’s team beat the Hungarian team, a European powerhouse, by 19:13 to win the championship. Last night’s "News Network" broadcast this good news.

When it comes to basketball games, the first thing we usually think of is 5X5, that is, five players from each side will play in four sessions with 10 minutes each (12 minutes for NBA and CBA). The public is much more unfamiliar with three-person basketball, and more may only stay in "knowing" that there is a KFC national youth three-person basketball championship challenge that has been held for 15 years in a row. Today, Lianjun will tell you about the "past life" of this sport.

Indeed, compared with the history of more than 100 years of five-a-side basketball competition, the popularity and popularity of three-a-side basketball, which was first played in world-class competition in 1992, is indeed much inferior. However, because it does not need much space (half of the five-person system), the single game time is short (10-16 minutes per game), and it is more suitable for training beginners’ technical movements and technical and tactical cooperation, it is very popular among young students.

In recent years, 3X3 basketball has made more and more appearances in the world. The FIBA Three-Man Basketball World Cup, which was won by the China women’s team, has been held for six times since it was first held in 2012. In 2017, the International Olympic Committee officially added the three-person basketball game to the Olympic Games.

After winning the World Cup, the China women’s team also successfully won the Olympic tickets, and we will see them again at the Tokyo Olympic Games next year.

"Many skills of three-person basketball and five-person basketball are the same. Whoever can put more balls into the basket will win." David Crocker, executive director of FIBA, once explained this sport. However, the difference between skills and actual combat also makes them have their own characteristics. From some angles, they can also be two completely different sports.

Only three players are present, which means it is difficult to distinguish the roles of "striker" and "defender", so everyone should get used to playing the role of generalist. The shrinking of the venue makes the confrontation more intense and the play faster. It is enough for each team to have four good players when three people play. Compared with the five-a-side basketball game, each team needs 8-12 excellent players to attack the medals. This game is undoubtedly more suspenseful, and anyone can become a winner.

Such suspense also makes it more possible for China to play three-person basketball in the future.

In the field of five-a-side basketball, China can’t be called a traditional strong team. Previously, China’s best performance in the world was the runner-up of the women’s team at the 1992 Barcelona Olympic Games. Although the men’s basketball team won the eighth place in four Olympic Games, it is always difficult to take a step forward.

But the situation is much better in three-person basketball. If you count the youth competitions, China won the championship as early as 2010. In the first World Youth Olympic Games, China U17 women’s three-person basketball team beat all the strong teams and finally won the gold medal. At last year’s Asian Games in Jakarta, the men’s and women’s teams of China swept the championship in this event. This makes us have more expectations for next year’s Olympic Games.

It is worth mentioning that, due to the good mass foundation, the three-person basketball game has more advantages in talent selection than the five-person basketball game, which also lays an excellent foundation for the future development of this project.

The four players of the men’s basketball team that won the championship in the Asian Games last year can be called "grassroots": Huang Wenwei, who scored the winner in the final, is a teacher of Guangzhou Institute of Physical Education, xiao hailiang is an employee of Dongguan Cultural and Sports Bureau, Zeng Bingqiang is a student of Guangdong University of Technology, and Chen Gong is from Hubei team, but so far, he has not played in the professional league. And they were able to get on the stage of the competition, all through the "I want to go to the Olympics" three-person basketball competition held in chinese basketball association at the beginning of last year.

After the two words "all the people" and "Olympic Games" are closely linked, China three-person basketball will surely enter a better era.